RDH12

Gene Symbol	RDH12
Entrez Gene	145226
Alt Symbol	LCA13, LCA3, RP53, SDR7C2
Species	Human
Gene Type	protein-coding
Description	retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
Other Description	all-trans and 9-cis retinol dehydrogenase|retinol dehydrogenase 12|retinol dehydrogenase 12, all-trans and 9-cis|short chain dehydrogenase/reductase family 7C member 2|short chain dehydrogenase/reductase family 7C, member 2
Swissprots	B2RDA2 Q8TAW6 Q96NR8
Accessions	EAW80951 Q96NR8 AK054835 BAB70811 AK315462 BAG37849 BC025724 AAH25724 DQ067457 DQ067458 HQ448700 ADQ33178 NM_152443 NP_689656
Function	Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity toward 9-cis and all-trans-retinol. Also involved in the metabolism of short-chain aldehydes. No steroid dehydrogenase activity detected. Might be the key enzyme in the formation of 11-cis-retinal from 11-cis-retinol during regeneration of the cone visual pigments. {ECO:0000269|PubMed:12226107}.
Tissue Specificity	Widely expressed, mostly in eye, kidney, brain, skeletal muscle and stomach.
Top Pathways	Retinol metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RDH12 Gene cDNA Clone - orb145022 from Biorbyt Prices $255.00 Sizes 10 μg Species Human

Human-RDH12-cDNA-Clone - DC05514 from Abgent, a WuXi AppTec company Prices $426.60 Sizes 10 µg Species Human Accession BC025724

RDH12 cDNA (ANA11283) - ANA11283 from Aviva Systems Biology Prices $189.00 Sizes 1 µg Accession BC025724

RDH12 cDNA (ANA11285) - ANA11285 from Aviva Systems Biology Prices $189.00 Sizes 1 µg Accession BC025724

RDH12 - MBS1272775 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC025724

Human RDH12 ORF Clone(NM_152443.2) - CDCL173477 from Creative Biomart Species Human Accession NM_152443.2

Human RDH12 Gene ORF cDNA clone in cloning vector - HG14101-G from Sino Biological Species Human

Human RDH12 Gene ORF cDNA clone expression plasmid - HG14101-UT from Sino Biological Species Human

Human RDH12 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG14101-ACR from Sino Biological Species Human

Human RDH12 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG14101-ANR from Sino Biological Species Human

Human RDH12 Gene ORF cDNA clone expression plasmid, C-HA tag - HG14101-CY from Sino Biological Species Human

Human RDH12 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG14101-ACG from Sino Biological Species Human

Human RDH12 Gene ORF cDNA clone expression plasmid, N-His tag - HG14101-NH from Sino Biological Species Human

Human RDH12 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG14101-NF from Sino Biological Species Human

Human RDH12 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG14101-NM from Sino Biological Species Human

Human RDH12 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG14101-CF from Sino Biological Species Human

Human RDH12 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG14101-CM from Sino Biological Species Human

Human RDH12 Gene ORF cDNA clone expression plasmid, C-His tag - HG14101-CH from Sino Biological Species Human

Human RDH12 Gene ORF cDNA clone expression plasmid, N-HA tag - HG14101-NY from Sino Biological Species Human

Human RDH12 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG14101-ANG from Sino Biological Species Human

human RDH12 ORF clone (NM_152443.2) - CDCH072696 from Creative biogene Species Human

Human RDH12 ORF Clone (BC025724) - CDCS417152 from Creative biogene Species Human Accession Q96NR8

Human RDH12 ORF clone (BC025724) - CDCB159387 from Creative biogene Species Human

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