RDH12

Gene Symbol RDH12
Entrez Gene 145226
Alt Symbol LCA13, LCA3, RP53, SDR7C2
Species Human
Gene Type protein-coding
Description retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
Other Description all-trans and 9-cis retinol dehydrogenase|retinol dehydrogenase 12|retinol dehydrogenase 12, all-trans and 9-cis|short chain dehydrogenase/reductase family 7C member 2|short chain dehydrogenase/reductase family 7C, member 2
Swissprots B2RDA2 Q8TAW6 Q96NR8
Accessions EAW80951 Q96NR8 AK054835 BAB70811 AK315462 BAG37849 BC025724 AAH25724 DQ067457 DQ067458 HQ448700 ADQ33178 NM_152443 NP_689656
Function Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity toward 9-cis and all-trans-retinol. Also involved in the metabolism of short-chain aldehydes. No steroid dehydrogenase activity detected. Might be the key enzyme in the formation of 11-cis-retinal from 11-cis-retinol during regeneration of the cone visual pigments. {ECO:0000269|PubMed:12226107}.
Tissue Specificity Widely expressed, mostly in eye, kidney, brain, skeletal muscle and stomach.
Top Pathways Retinol metabolism

RDH12 CRISPR/Cas9 KO Plasmid (h) - sc-409042 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDH12 HDR Plasmid (h) - sc-409042-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDH12 Double Nickase Plasmid (h) - sc-409042-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDH12 Double Nickase Plasmid (h2) - sc-409042-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDH12 CRISPR Activation Plasmid (h) - sc-409042-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDH12 CRISPR Activation Plasmid (h2) - sc-409042-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDH12 Lentiviral Activation Particles (h) - sc-409042-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDH12 Lentiviral Activation Particles (h2) - sc-409042-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDH12 siRNA (h) - sc-76378 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RDH12 shRNA Plasmid (h) - sc-76378-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RDH12 shRNA (h) Lentiviral Particles - sc-76378-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU051081 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2542 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2542 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04922 from Sigma-Aldrich

Category miRNA

RDH12 siRNA (Human) - CRJ5424 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RDH12 - MBS8226234 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human RDH12 (NM_152443.2) - SHH391464 from Creative biogene

Category siRNA
Species Reactivities Human

Human RDH12 siRNA - orb275925 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RDH12 shRNA Plasmid (Human) - CHJ5424 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

RDH12 miRNA 3'UTR clone - MiUTR3H-10255 from Creative biogene

Species Reactivities Human
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