RDH12

Gene Symbol	RDH12
Entrez Gene	145226
Alt Symbol	LCA13, LCA3, RP53, SDR7C2
Species	Human
Gene Type	protein-coding
Description	retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
Other Description	all-trans and 9-cis retinol dehydrogenase|retinol dehydrogenase 12|retinol dehydrogenase 12, all-trans and 9-cis|short chain dehydrogenase/reductase family 7C member 2|short chain dehydrogenase/reductase family 7C, member 2
Swissprots	B2RDA2 Q8TAW6 Q96NR8
Accessions	EAW80951 Q96NR8 AK054835 BAB70811 AK315462 BAG37849 BC025724 AAH25724 DQ067457 DQ067458 HQ448700 ADQ33178 NM_152443 NP_689656
Function	Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity toward 9-cis and all-trans-retinol. Also involved in the metabolism of short-chain aldehydes. No steroid dehydrogenase activity detected. Might be the key enzyme in the formation of 11-cis-retinal from 11-cis-retinol during regeneration of the cone visual pigments. {ECO:0000269|PubMed:12226107}.
Tissue Specificity	Widely expressed, mostly in eye, kidney, brain, skeletal muscle and stomach.
Top Pathways	Retinol metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RDH12 full length protein - ab132828 from Abcam Category Protein Source Wheat germ Species Human

Human RDH12 protein fragment - ab119458 from Abcam Category Protein Source E. coli Species Human

LCA3 / SPATA7 Antibody Blocking Peptide - LS-E1658 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LCA3 / SPATA7 Antibody Blocking Peptide - LS-E20889 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RDH12 / LCA3 Antibody Blocking Peptide - LS-E19098 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RDH12 / LCA3 Antibody Blocking Peptide - LS-E19099 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RDH12 Partial Recombinant Protein - H00145226-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

RDH12 Recombinant Protein - H00145226-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human RDH12 Protein - NBP1-78870 from Novus Biologicals Category Protein Prices $349.00 Sizes 50 µg Source E. coli Species Human

RDH12-Antibody-N-term-Blocking-peptide - BP10748a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human RDH12 protein - orb246268 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human RDH12 protein - orb169180 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

RDH12 Blocking Peptide - 33R-3754 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

RDH12 Blocking Peptide - 33R-1308 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

RDH12 protein (His tag) - 80R-2113 from Fitzgerald Category Protein Prices $365.00 Sizes 50 µg Source E.coli

RDH12 (39-316, His-tag) - AR50196PU-N from Acris Antibodies Category Protein Prices $1,010.00 Sizes 250 µg Source E. coli Species Human

RDH12 (39-316, His-tag) - AR50196PU-S from Acris Antibodies Category Protein Prices $410.00 Sizes 50 µg Source E. coli Species Human

RDH12 - H00145226-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

RDH12 - H00145226-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

RDH12 - H00145226-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

RDH12 - H00145226-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Retinol Dehydrogenase 12, Human Recombinant - 228-12384-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

Recombinant Human Retinol Dehydrogenase 12 - 228-12384-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source E.coli. Species Human

Recombinant Human Retinol Dehydrogenase 12 - 228-12384-3 from RayBiotech Category Protein Source E.coli. Species Human

RDH12, 39-316aa, Human, His tag, E.coli - 01-P1371 from ARP American Research Products Category Protein Prices $179.00, $449.00, $1,089.00 Sizes 10 µg, 50 µg, 250 µg Species Human

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