RDH12

Gene Symbol RDH12
Entrez Gene 145226
Alt Symbol LCA13, LCA3, RP53, SDR7C2
Species Human
Gene Type protein-coding
Description retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
Other Description all-trans and 9-cis retinol dehydrogenase|retinol dehydrogenase 12|retinol dehydrogenase 12, all-trans and 9-cis|short chain dehydrogenase/reductase family 7C member 2|short chain dehydrogenase/reductase family 7C, member 2
Swissprots B2RDA2 Q8TAW6 Q96NR8
Accessions EAW80951 Q96NR8 AK054835 BAB70811 AK315462 BAG37849 BC025724 AAH25724 DQ067457 DQ067458 HQ448700 ADQ33178 NM_152443 NP_689656
Function Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity toward 9-cis and all-trans-retinol. Also involved in the metabolism of short-chain aldehydes. No steroid dehydrogenase activity detected. Might be the key enzyme in the formation of 11-cis-retinal from 11-cis-retinol during regeneration of the cone visual pigments. {ECO:0000269|PubMed:12226107}.
Tissue Specificity Widely expressed, mostly in eye, kidney, brain, skeletal muscle and stomach.
Top Pathways Retinol metabolism

RDH12 (H-40) - sc-98347 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
RDH12 (H-40): sc-98347. Western blot analysis of RDH12 expression in non-transfected: sc-110760 (A) and human RDH12 transfected: sc-114062 (B) 293 whole cell lysates.

RDH12 (I-19) - sc-79019 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
RDH12 (I-19): sc-79019. Western blot analysis of RDH12 expression in non-transfected: sc-110760 (A) and human RDH12 transfected: sc-114062 (B) 293 whole cell lysates.

RDH12 (W-17) - sc-79023 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
RDH12 (W-17): sc-79023. Western blot analysis of RDH12 expression in human platelet extract.

Anti-RDH12 antibody - ab173449 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-RDH12 antibody (ab173449) at 1 µg/mlLane 1 : RDH12 transfected 293T cell line lysateLane 2 : Non-transfected 293T cell line lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Rabbit IgG (H+L), Peroxidase Conjugated at 1/7500 dilutiondeveloped using the ECL technique

Anti-RDH12 antibody - ab72874 from Abcam

Prices $359.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-RDH12 antibody (ab72874) at 1/500 dilutionLane 1 : RDH12 transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

Anti-RDH12 antibody - ab87038 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-RDH12 antibody (ab87038) at 1 µg/ml (in 5% skim milk / PBS buffer) + Transfected 293T cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-RDH12 / LCA3 Antibody (aa179-228) - LS-C102499 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RDH12 antibody LS-C102499 Western blot of Transfected 293T cell lysate.

Anti-RDH12 / LCA3 Antibody (aa215-264) - LS-C111452 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RDH12 antibody LS-C111452 Western blot of Fetal Intestine lysate.

RDH12 Antibody - NBP1-58017 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RDH12 Antibody [NBP1-58017] - Human Fetal Intestine, concentration 0.2-1 ug/ml.

RDH12 Antibody - NBP1-57955 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RDH12 Antibody [NBP1-57955] - Transfected 293T cell lysate, concentration 0.2-1 ug/ml.

RDH12 Antibody (1E11) - H00145226-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1E11
Immunocytochemistry/Immunofluorescence: RDH12 Antibody (1E11) [H00145226-M01] - Analysis of monoclonal antibody to RDH12 on HeLa cell. Antibody concentration 10 ug/ml.

RDH12 Antibody - H00145226-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: RDH12 Antibody [H00145226-D01P] - Analysis of RDH12 expression in transfected 293T cell line by RDH12 polyclonal antibody.Lane 1: RDH12 transfected lysate(35.10 KDa).Lane 2: Non-transfected lysate.

RDH12 Antibody - H00145226-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-RDH12 (286-300) antibody produced in rabbit - SAB1103294 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human RDH12 was separated on SDS-PAGE, blotted with Anti-RDH12 (286-300) (<B>Cat. No. SAB1103294</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000

Anti-RDH12 antibody produced in rabbit - SAB2103616 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-RDH12, antibody produced in rabbit: <B>Cat. No. SAB2103616</B>: Immunoblotting analysis of RDH12 in fetal intestine tissue lysate with RDH12 anitbody at 1 μg/mL.

Monoclonal Anti-RDH12 antibody produced in mouse - SAB1402013 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1E11
<B>Immunofluorescence</B><BR/>Monoclonal Anti-RDH12: <B>Cat. No. SAB1402013</B>: Antibody concentration: 10 μg/mL using HeLa cell.

RDH12 antibody - middle region (ARP52972_P050) - ARP52972_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RDH12 antibody - middle region (ARP52973_P050) - ARP52973_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

RDH12 antibody - orb40946 from Biorbyt

Prices $357.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal
Immunohistochemical staining of human skeletal muscle tissue using RDH12 antibody

RDH12 antibody - 70R-19839 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

RDH12 antibody - 70R-5393 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

RDH12 antibody - 70R-5450 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

RDH12 antibody - 13289-3-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Human skeletal muscle were subjected to SDS PAGE followed by western blot with 13289-3-AP(RDH12 Antibody) at dilution of 1:1000

RDH12 antibody - H00145226-B01P from Acris Antibodies

Prices $360.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

RDH12 antibody - H00145226-D01P from Acris Antibodies

Prices $390.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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