INSRR

Gene Symbol INSRR
Entrez Gene 3645
Alt Symbol IRR
Species Human
Gene Type protein-coding
Description insulin receptor-related receptor
Other Description IR-related receptor|insulin receptor-related protein
Swissprots P14616 Q5VZS3 O60724
Accessions EAW52903 EAW52904 P14616 AF064078 AAC17167 AK310760 BC156081 AAI56082 BC157044 AAI57045 J05046 AAC31759 JQ991924 AFM93766 NM_014215 NP_055030
Function Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB. {ECO:0000269|PubMed:21641549}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Top Pathways Prostate cancer, Regulation of actin cytoskeleton

IRRα (A-20) - sc-19850 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

IRRα (L-20) - sc-19851 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

IRRβ (E-20) - sc-19854 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
IRRβ (E-20): sc-19854. Western blot analysis of IRR precursor expression in SK-N-SH (A) and T98G (B) whole cell lysates. Note lack of expression of β subunit.

IRRβ (D-16) - sc-19855 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

IRR (I-63) - sc-100303 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
IRR (I-63): sc-100303. Western blot analysis of IRR expression in HeLa whole cell lysate.

Anti-Insulin Receptor R antibody - ab5504 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

Anti-Insulin Receptor R antibody - ab5501 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Insulin Receptor R antibody - ab123799 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Insulin Receptor R antibody (ab123799) at 1/100 dilution + A549 cell line lysates at 35 µg

Anti-Insulin Receptor R antibody [EP327Y] - ab40782 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP327Y
All lanes : Anti-Insulin Receptor R antibody [EP327Y] (ab40782) at 1/2000 dilutionLane 1 : PC12Lane 2 : MCF7Lane 3 : HelaLane 4 : SHSY5YLysates/proteins at 10 µg per lane.

Anti-Insulin Receptor R antibody [MM077125K51] - ab201648 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM077125K51

Anti-INSRR Antibody (aa1228-1255) - LS-C164425 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Mouse Insrr Antibody western blot of mouse heart tissue lysates (35 ug/lane). The Insrr antibody detected the Insrr protein (arrow).

Anti-INSRR Antibody (clone 6E6) - LS-C133272 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6E6
Immunoperoxidase of monoclonal antibody to INSRR on formalin-fixed paraffin-embedded human esophagus. [antibody concentration 1 ug/ml]

Anti-INSRR Antibody (aa668-702) - LS-C344497 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysates from A549, HeLa, MCF-7, SH-SY5Y, SW480 cell line (from left to right) with INSRR Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20 ug per lane.

Anti-INSRR Antibody (aa1295-1289) - LS-C344454 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysate from rat brain tissue with Mouse Insrr Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20 ug.

Anti-INSRR Antibody (aa1228-1255, AP) - LS-C260277 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-INSRR Antibody (aa1228-1255, APC) - LS-C260278 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-INSRR Antibody (aa1228-1255, Biotin) - LS-C260279 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-INSRR Antibody (aa1228-1255, FITC) - LS-C260280 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-INSRR Antibody (aa1228-1255, Azide-free, HRP) - LS-C260281 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-INSRR Antibody (aa1228-1255, PE) - LS-C260283 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-INSRR Antibody (C-Terminus, AP) - LS-C278375 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-INSRR Antibody (C-Terminus, APC) - LS-C278376 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-INSRR Antibody (C-Terminus, PE) - LS-C278383 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-INSRR Antibody (C-Terminus, FITC) - LS-C278382 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-INSRR Antibody (C-Terminus, Biotin) - LS-C278380 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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