Gene Symbol | INSRR |
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Entrez Gene | 3645 |
Alt Symbol | IRR |
Species | Human |
Gene Type | protein-coding |
Description | insulin receptor-related receptor |
Other Description | IR-related receptor|insulin receptor-related protein |
Swissprots | P14616 Q5VZS3 O60724 |
Accessions | EAW52903 EAW52904 P14616 AF064078 AAC17167 AK310760 BC156081 AAI56082 BC157044 AAI57045 J05046 AAC31759 JQ991924 AFM93766 NM_014215 NP_055030 |
Function | Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB. {ECO:0000269|PubMed:21641549}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | Prostate cancer, Regulation of actin cytoskeleton |
Active Insulin Receptor R protein fragment - ab69988 from Abcam
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Human Insulin Receptor R protein fragment - ab158768 from Abcam
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INSRR Antibody Blocking Peptide - LS-E3584 from LifeSpan Bioscience
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INSRR Antibody Blocking Peptide - LS-E9155 from LifeSpan Bioscience
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INSRR Antibody Blocking Peptide - LS-E9156 from LifeSpan Bioscience
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INSRR/IR-related receptor Partial Recombinant Protein - H00003645-Q01 from Novus Biologicals
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INSRR/IR-related receptor Peptide - P2689 from Novus Biologicals
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INSRR/IR-related receptor Peptide - P2688 from Novus Biologicals
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Mouse-Insrr-Antibody-C-term-Blocking-Peptide - BP14784b from Abgent, a WuXi AppTec company
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Insulin-Receptor-R-Antibody-C-term-Blocking-peptide - BP7654b from Abgent, a WuXi AppTec company
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Insulin-Receptor-R-Antibody-N-term-Blocking-peptide - BP7654a from Abgent, a WuXi AppTec company
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INSRR / IRR - H00003645-Q01-10 from Acris Antibodies
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INSRR / IRR - H00003645-Q01-25 from Acris Antibodies
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INSRR / IRR - P5567 from Acris Antibodies
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Recombinant Human Insulin Receptor-Related Receptor, GAT-tagged - INSRR-1865H from Creative Biomart
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Recombinant Human Insulin Receptor-related Receptor, GST-tagged, Active - INSRR-334H from Creative Biomart
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Recombinant Human INSRR - INSRR-26859TH from Creative Biomart
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IRR Protein, active, 250 µg - 14-645M from EMD Millipore
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IRR Protein, active, 10 µg - 14-645 from EMD Millipore
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Recombinant Human Insulin receptor-related protein(INSRR) - CSB-YP011755HU CSB-EP011755HU CSB-BP011755HU CSB-MP011755HU from Cusabio
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INSRR / IRR - TP324956 from Acris Antibodies
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INSRR / IRR (C-term DDK tag) - TP710106 from Acris Antibodies
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Recombinant Human INSRR (aa 944-1297) GST - CSI12163 from Cell Science
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INSRR/IR-related receptor Recombinant Protein Antigen - NBP1-87704PEP from Novus Biologicals
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INSRR-Blocking-PeptideCenter - BP19813c from Abgent, a WuXi AppTec company
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