Gene Symbol | INSRR |
---|---|
Entrez Gene | 3645 |
Alt Symbol | IRR |
Species | Human |
Gene Type | protein-coding |
Description | insulin receptor-related receptor |
Other Description | IR-related receptor|insulin receptor-related protein |
Swissprots | P14616 Q5VZS3 O60724 |
Accessions | EAW52903 EAW52904 P14616 AF064078 AAC17167 AK310760 BC156081 AAI56082 BC157044 AAI57045 J05046 AAC31759 JQ991924 AFM93766 NM_014215 NP_055030 |
Function | Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB. {ECO:0000269|PubMed:21641549}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | Prostate cancer, Regulation of actin cytoskeleton |
IRRα/β siRNA (h) - sc-40081 from Santa Cruz Biotechnology
|
||||||||
IRRβ shRNA Plasmid (h) - sc-40081-SH from Santa Cruz Biotechnology
|
||||||||
IRRβ shRNA (h) Lentiviral Particles - sc-40081-V from Santa Cruz Biotechnology
|
||||||||
INSRR/IR-related receptor RNAi - H00003645-R04 from Novus Biologicals
|
||||||||
MISSION® siRNA - SIHK0969 from Sigma-Aldrich
|
||||||||
MISSION® siRNA - SIHK0968 from Sigma-Aldrich
|
||||||||
MISSION® siRNA - SIHK0967 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN10708 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10708 from Sigma-Aldrich
|
||||||||
INSRR siRNA (Human) - CRH2444 from Cohesion Biosciences
|
||||||||
INSRR - MBS8239891 from MyBioSource
|
||||||||
shRNA set against Human INSRR (NM_014215.2) - SHH319917 from Creative biogene
|
||||||||
Human INSRR siRNA - orb262946 from Biorbyt
|
||||||||
INSRR shRNA Plasmid (Human) - CHH2444 from Cohesion Biosciences
|
||||||||
INSRR miRNA 3'UTR clone - MiUTR4H-TG04541 from Creative biogene
|