| Gene Symbol |
SND1
|
| Entrez Gene |
27044
|
| Alt Symbol |
TDRD11, p100
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
staphylococcal nuclease and tudor domain containing 1
|
| Other Description |
100 kDa coactivator|EBNA-2 co-activator (100kD)|EBNA2 coactivator p100|SND1-BRAF fusion|Tudor-SN|p100 EBNA2 co-activator|p100 co-activator|staphylococcal nuclease domain containing 1|staphylococcal nuclease domain-containing protein 1|tudor domain-containing protein 11
|
| Swissprots |
Q7KZF4 Q96AG0 Q13122
|
| Accessions |
EAW83635 EAW83636 EAW83637 Q7KZF4 AB209510 BAD92747 AK096583 BAG53329 AK304181 BAG65061 AK309014 AK312313 BAG35238 AY273894 AAP31683 BC017180 AAH17180 BC020423 BE799345 BM149154 BQ217773 BT009785 AAP88787 DQ893632 ABM84558 DQ895529 ABM86455 U22055 AAA80488 XM_011516051 XP_011514353 NM_014390 NP_055205
|
| Function |
Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2). {ECO:0000269|PubMed:7651391}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:17081065}. Nucleus {ECO:0000269|PubMed:17081065}. Melanosome {ECO:0000269|PubMed:17081065}. Note=In IL-4 stimulated cells colocalizes with STAT6 in the nucleus. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
|
| Tissue Specificity |
Ubiquitously expressed. {ECO:0000269|PubMed:7651391}.
|
| Top Pathways |
Viral carcinogenesis, Epstein-Barr virus infection
|