Gene Symbol | SND1 |
---|---|
Entrez Gene | 27044 |
Alt Symbol | TDRD11, p100 |
Species | Human |
Gene Type | protein-coding |
Description | staphylococcal nuclease and tudor domain containing 1 |
Other Description | 100 kDa coactivator|EBNA-2 co-activator (100kD)|EBNA2 coactivator p100|SND1-BRAF fusion|Tudor-SN|p100 EBNA2 co-activator|p100 co-activator|staphylococcal nuclease domain containing 1|staphylococcal nuclease domain-containing protein 1|tudor domain-containing protein 11 |
Swissprots | Q7KZF4 Q96AG0 Q13122 |
Accessions | EAW83635 EAW83636 EAW83637 Q7KZF4 AB209510 BAD92747 AK096583 BAG53329 AK304181 BAG65061 AK309014 AK312313 BAG35238 AY273894 AAP31683 BC017180 AAH17180 BC020423 BE799345 BM149154 BQ217773 BT009785 AAP88787 DQ893632 ABM84558 DQ895529 ABM86455 U22055 AAA80488 XM_011516051 XP_011514353 NM_014390 NP_055205 |
Function | Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2). {ECO:0000269|PubMed:7651391}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:17081065}. Nucleus {ECO:0000269|PubMed:17081065}. Melanosome {ECO:0000269|PubMed:17081065}. Note=In IL-4 stimulated cells colocalizes with STAT6 in the nucleus. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:7651391}. |
Top Pathways | Viral carcinogenesis, Epstein-Barr virus infection |