Gene Symbol | SND1 |
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Entrez Gene | 27044 |
Alt Symbol | TDRD11, p100 |
Species | Human |
Gene Type | protein-coding |
Description | staphylococcal nuclease and tudor domain containing 1 |
Other Description | 100 kDa coactivator|EBNA-2 co-activator (100kD)|EBNA2 coactivator p100|SND1-BRAF fusion|Tudor-SN|p100 EBNA2 co-activator|p100 co-activator|staphylococcal nuclease domain containing 1|staphylococcal nuclease domain-containing protein 1|tudor domain-containing protein 11 |
Swissprots | Q7KZF4 Q96AG0 Q13122 |
Accessions | EAW83635 EAW83636 EAW83637 Q7KZF4 AB209510 BAD92747 AK096583 BAG53329 AK304181 BAG65061 AK309014 AK312313 BAG35238 AY273894 AAP31683 BC017180 AAH17180 BC020423 BE799345 BM149154 BQ217773 BT009785 AAP88787 DQ893632 ABM84558 DQ895529 ABM86455 U22055 AAA80488 XM_011516051 XP_011514353 NM_014390 NP_055205 |
Function | Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2). {ECO:0000269|PubMed:7651391}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:17081065}. Nucleus {ECO:0000269|PubMed:17081065}. Melanosome {ECO:0000269|PubMed:17081065}. Note=In IL-4 stimulated cells colocalizes with STAT6 in the nucleus. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:7651391}. |
Top Pathways | Viral carcinogenesis, Epstein-Barr virus infection |
TudorSN (C-9) - sc-271590 from Santa Cruz Biotechnology
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TudorSN (F-5) - sc-166676 from Santa Cruz Biotechnology
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TudorSN (N-13) - sc-34757 from Santa Cruz Biotechnology
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TudorSN (H-300) - sc-67128 from Santa Cruz Biotechnology
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TudorSN (E-11) - sc-166518 from Santa Cruz Biotechnology
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TudorSN (C-17) - sc-34753 from Santa Cruz Biotechnology
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TudorSN (F-16) - sc-34755 from Santa Cruz Biotechnology
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Anti-SND1 antibody - ab123800 from Abcam
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Anti-SND1 antibody [2D7B12,2D12B12A4] - ab70422 from Abcam
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Anti-SND1 Antibody (aa449-478, AP) - LS-C269769 from LifeSpan Bioscience
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Anti-SND1 Antibody (aa449-478, APC) - LS-C269770 from LifeSpan Bioscience
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Anti-SND1 Antibody (aa449-478, Biotin) - LS-C269772 from LifeSpan Bioscience
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Anti-SND1 Antibody (aa449-478, FITC) - LS-C269773 from LifeSpan Bioscience
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Anti-SND1 Antibody (aa449-478, Azide-free, HRP) - LS-C269774 from LifeSpan Bioscience
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Anti-SND1 Antibody (aa449-478, PE) - LS-C269777 from LifeSpan Bioscience
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Anti-SND1 Antibody (aa448-478) - LS-C325227 from LifeSpan Bioscience
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Anti-SND1 Antibody (aa213-262) - LS-C31447 from LifeSpan Bioscience
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Anti-SND1 Antibody (Internal) - LS-C345731 from LifeSpan Bioscience
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Anti-SND1 Antibody - LS-C334352 from LifeSpan Bioscience
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Anti-SND1 Antibody (clone 287C1a) - LS-C342717 from LifeSpan Bioscience
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Anti-SND1 Antibody (clone 2D7) - LS-C108728 from LifeSpan Bioscience
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Anti-SND1 Antibody (aa449-478) - LS-C161343 from LifeSpan Bioscience
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Anti-SND1 Antibody (aa100-150) - LS-C289594 from LifeSpan Bioscience
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Monoclonal Anti-SND1 antibody produced in mouse - SAB5300017 from Sigma-Aldrich
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Anti-SND1 antibody produced in rabbit - SAB4200470 from Sigma-Aldrich
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