Gene Symbol | SND1 |
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Entrez Gene | 27044 |
Alt Symbol | TDRD11, p100 |
Species | Human |
Gene Type | protein-coding |
Description | staphylococcal nuclease and tudor domain containing 1 |
Other Description | 100 kDa coactivator|EBNA-2 co-activator (100kD)|EBNA2 coactivator p100|SND1-BRAF fusion|Tudor-SN|p100 EBNA2 co-activator|p100 co-activator|staphylococcal nuclease domain containing 1|staphylococcal nuclease domain-containing protein 1|tudor domain-containing protein 11 |
Swissprots | Q7KZF4 Q96AG0 Q13122 |
Accessions | EAW83635 EAW83636 EAW83637 Q7KZF4 AB209510 BAD92747 AK096583 BAG53329 AK304181 BAG65061 AK309014 AK312313 BAG35238 AY273894 AAP31683 BC017180 AAH17180 BC020423 BE799345 BM149154 BQ217773 BT009785 AAP88787 DQ893632 ABM84558 DQ895529 ABM86455 U22055 AAA80488 XM_011516051 XP_011514353 NM_014390 NP_055205 |
Function | Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2). {ECO:0000269|PubMed:7651391}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:17081065}. Nucleus {ECO:0000269|PubMed:17081065}. Melanosome {ECO:0000269|PubMed:17081065}. Note=In IL-4 stimulated cells colocalizes with STAT6 in the nucleus. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:7651391}. |
Top Pathways | Viral carcinogenesis, Epstein-Barr virus infection |
TudorSN CRISPR/Cas9 KO Plasmid (h) - sc-403949 from Santa Cruz Biotechnology
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TudorSN HDR Plasmid (h) - sc-403949-HDR from Santa Cruz Biotechnology
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TudorSN Double Nickase Plasmid (h) - sc-403949-NIC from Santa Cruz Biotechnology
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TudorSN Double Nickase Plasmid (h2) - sc-403949-NIC-2 from Santa Cruz Biotechnology
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TudorSN CRISPR Activation Plasmid (h) - sc-403949-ACT from Santa Cruz Biotechnology
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TudorSN CRISPR Activation Plasmid (h2) - sc-403949-ACT-2 from Santa Cruz Biotechnology
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TudorSN Lentiviral Activation Particles (h) - sc-403949-LAC from Santa Cruz Biotechnology
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TudorSN Lentiviral Activation Particles (h2) - sc-403949-LAC-2 from Santa Cruz Biotechnology
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TudorSN siRNA (h) - sc-45514 from Santa Cruz Biotechnology
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TudorSN shRNA Plasmid (h) - sc-45514-SH from Santa Cruz Biotechnology
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TudorSN shRNA (h) Lentiviral Particles - sc-45514-V from Santa Cruz Biotechnology
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SND1 RNAi - H00027044-R01 from Novus Biologicals
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MISSION® esiRNA - EHU054581 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19864 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19864 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05189 from Sigma-Aldrich
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SND1 siRNA (Human) - CRH8940 from Cohesion Biosciences
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SND1 - MBS8239624 from MyBioSource
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shRNA set against Human SND1 (NM_014390.2) - SHH414040 from Creative biogene
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shRNA set against Human SND1(NM_014390.2) - SHL021580 from Creative biogene
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Human SND1 siRNA - orb269442 from Biorbyt
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SND1 shRNA Plasmid (Human) - CHH8940 from Cohesion Biosciences
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SND1 miRNA 3'UTR clone - MiUTR1H-09687 from Creative biogene
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