Gene Symbol | HAS1 |
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Entrez Gene | 3036 |
Alt Symbol | HAS |
Species | Human |
Gene Type | protein-coding |
Description | hyaluronan synthase 1 |
Other Description | HA synthase 1|hyaluronate synthase 1|hyaluronic acid synthase 1 |
Swissprots | Q9NS49 Q14470 Q92839 |
Accessions | AAF87845 EAW72038 EAW72039 Q92839 AM904814 CAP17884 AY916554 AAY52130 AY916555 AAY52131 AY916556 AAY52132 BC035837 AAH35837 BX371636 D84424 BAA12351 DQ891219 ABM82145 DQ894402 ABM85328 U59269 AAC50706 XM_011526884 XP_011525186 NM_001297436 NP_001284365 NM_001523 NP_001514 |
Function | Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction. Also able to catalyze the synthesis of chito- oligosaccharide depending on the substrate (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Widely expressed. Highly expressed in ovary followed by spleen, thymus, prostate, testes and large intestine. Weakly expressed in small intestine. {ECO:0000269|PubMed:8651928}. |
HAS1 / HAS Antibody Blocking Peptide - LS-E7650 from LifeSpan Bioscience
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HAS1 / HAS Antibody Blocking Peptide - LS-E23116 from LifeSpan Bioscience
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HAS1-Antibody-Center-Blocking-Peptide - BP4928c from Abgent, a WuXi AppTec company
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Hyaluronan Synthase 1 (HAS1), Human - 20-8517 from ARP American Research Products
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HAS1 fusion protein - ag8073 from Proteintech Group
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HAS1 fusion protein - ag4901 from Proteintech Group
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Recombinant Human HAS - HAS-252H from Creative Biomart
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Recombinant Human HAS - HAS-75H from Creative Biomart
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Recombinant Hyaluronan Synthase 1 (HAS1) - RPC520Hu01 from Uscn Life Science Inc.
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Recombinant Hyaluronan Synthase 1 (HAS1) - RPC520Ra01 from Uscn Life Science Inc.
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Recombinant Hyaluronan Synthase 1 (HAS1) - RPC520Ra51 from Uscn Life Science Inc.
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Recombinant Hyaluronan Synthase 1 (HAS1) - RPC520Hu01 from Cloud-clone
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Hyaluronan synthase 1 Recombinant Protein Antigen - NBP2-39087PEP from Novus Biologicals
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HAS1 Peptide, Human - M34GP06840H from Creative Peptides
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HAS protein - orb86133 from Biorbyt
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Hyaluronan synthase 1 (HAS1), Recombinant Protein - MBS7016497 from MyBioSource
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Recombinant Hyaluronan Synthase 1 (HAS1) - RPU55330 from Biomatik
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Recombinant Human HSA protein, His-tagged, low endotoxin - HAS-370H from Creative Biomart
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Recombinant Human HAS1 Protein, GST-tagged - HAS1-4583H from Creative Biomart
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