Gene Symbol | HAS1 |
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Entrez Gene | 3036 |
Alt Symbol | HAS |
Species | Human |
Gene Type | protein-coding |
Description | hyaluronan synthase 1 |
Other Description | HA synthase 1|hyaluronate synthase 1|hyaluronic acid synthase 1 |
Swissprots | Q9NS49 Q14470 Q92839 |
Accessions | AAF87845 EAW72038 EAW72039 Q92839 AM904814 CAP17884 AY916554 AAY52130 AY916555 AAY52131 AY916556 AAY52132 BC035837 AAH35837 BX371636 D84424 BAA12351 DQ891219 ABM82145 DQ894402 ABM85328 U59269 AAC50706 XM_011526884 XP_011525186 NM_001297436 NP_001284365 NM_001523 NP_001514 |
Function | Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction. Also able to catalyze the synthesis of chito- oligosaccharide depending on the substrate (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Widely expressed. Highly expressed in ovary followed by spleen, thymus, prostate, testes and large intestine. Weakly expressed in small intestine. {ECO:0000269|PubMed:8651928}. |
HAS1 (C-14) - sc-23145 from Santa Cruz Biotechnology
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HAS1 (G-17) - sc-34021 from Santa Cruz Biotechnology
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HAS1 (R-15) - sc-34020 from Santa Cruz Biotechnology
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HAS1/2/3 (E-16) - sc-23146 from Santa Cruz Biotechnology
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Anti-Hyaluronan synthase 1 antibody - ab198846 from Abcam
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Anti-Hyaluronan synthase 1 antibody - ab128321 from Abcam
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Anti-Hyaluronan synthase 1 antibody - ab75329 from Abcam
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Anti-Hyaluronan synthase 1 antibody [3E10] - ab104864 from Abcam
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Anti-HAS1 / HAS Antibody (aa166-193, AP) - LS-C258246 from LifeSpan Bioscience
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Anti-HAS1 / HAS Antibody (aa166-193, APC) - LS-C258247 from LifeSpan Bioscience
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Anti-HAS1 / HAS Antibody (aa166-193, Biotin) - LS-C258248 from LifeSpan Bioscience
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Anti-HAS1 / HAS Antibody (aa171-220) - LS-C151522 from LifeSpan Bioscience
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Anti-HAS1 / HAS Antibody (aa166-193, FITC) - LS-C258249 from LifeSpan Bioscience
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Anti-HAS1 / HAS Antibody (aa166-193, Azide-free, HRP) - LS-C258250 from LifeSpan Bioscience
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Anti-HAS1 / HAS Antibody (aa166-193, PE) - LS-C258251 from LifeSpan Bioscience
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Anti-HAS1 / HAS Antibody (aa164-421, FITC) - LS-C302852 from LifeSpan Bioscience
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Anti-HAS1 / HAS Antibody (aa164-421, Biotin) - LS-C300554 from LifeSpan Bioscience
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Anti-HAS1 / HAS Antibody (aa170-200) - LS-C321874 from LifeSpan Bioscience
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Anti-HAS1 / HAS Antibody (aa166-193) - LS-C166791 from LifeSpan Bioscience
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Anti-HAS1 / HAS Antibody (aa164-421) - LS-C294540 from LifeSpan Bioscience
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Anti-HAS1 / HAS Antibody (clone 3E10) - LS-C169231 from LifeSpan Bioscience
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Hyaluronan synthase 1 Antibody (3E10) - NBP1-51635 from Novus Biologicals
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Hyaluronan synthase 1 Antibody - NBP2-39087 from Novus Biologicals
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HAS1 Polyclonal Antibody - bs-2946R from Bioss
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Anti-HAS1 antibody produced in rabbit - SAB4300848 from Sigma-Aldrich
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