MGAT4A

Gene Symbol	MGAT4A
Entrez Gene	11320
Alt Symbol	GNT-IV, GNT-IVA, GnT-4a
Species	Human
Gene Type	protein-coding
Description	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
Other Description	N-acetylglucosaminyltransferase IVa\|N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVa\|UDP-GlcNAc:a-1,3-D-mannoside b-1,4-acetylglucosaminyltransferase IV\|UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVa\|UDP-N-acetylglucosamine:alpha1,3-d-mannoside beta1,4-N-acetylglucosaminyltransferase\|alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A\|alpha-1,3-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase\|glcNAc-T IVa\|mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isoenzyme A
Swissprots	Q53S97 D3DVH6 Q9UM21 Q86Z15 B4E2R6 E9PEN2
Accessions	AAY14976 AAY24092 BAC55023 EAX01896 EAX01897 EAX01898 Q9UM21 AB000616 BAA86388 AK092952 AK128366 AK291533 BAF84222 AK304393 BAG65228 AK309852 AK314024 AW138839 BC127107 AAI27108 BC127108 AAI27109 NM_001160154 NP_001153626 NM_012214 NP_036346
Function	Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N- linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Involved in glucose transport by mediating SLC2A2/GLUT2 glycosylation, thereby controlling cell-surface expression of SLC2A2 in pancreatic beta cells.
Subcellular Location	Alpha-1,3-mannosyl-glycoprotein 4-beta-N- acetylglucosaminyltransferase A: Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity	Expressed in pancreas, spleen, thymus, prostate, small intestine, peripheral blood leukocytes and lymph node. Strongly overexpressed in choriocarcinoma cancer cell lines. Down-regulated in pancreatic cancer. {ECO:0000269\|PubMed:10024668}.
Top Pathways	N-Glycan biosynthesis

GnT-IVA (E-12) - sc-168022 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

GnT-IVA (N-14) - sc-168023 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

GnT-IVA (M-71) - sc-100785 from Santa Cruz Biotechnology

Prices	$295.00
Sizes	100 µg/ml
Host	Mouse
Clonality	Monoclonal

GnT-IVA (M-71): sc-100785. Western blot analysis of GnT-IVA expression in Jurkat whole cell lysate.

Anti-MGAT4A Antibody (aa436-536, Azide-free) - LS-C327866 from LifeSpan Bioscience

Host	Mouse
Clonality	Monoclonal

Anti-MGAT4A Antibody (clone 4H4) - LS-C133686 from LifeSpan Bioscience

Prices	$355.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	4H4

Immunoperoxidase of monoclonal antibody to MGAT4A on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 0.2 ug/ml]

MGAT4A Antibody - NBP2-17285 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: MGAT4A Antibody [NBP2-17285] - Sample (30 ug of whole cell lysate) A: Hela 7. 5% SDS PAGE gel, diluted at 1:1000.

MGAT4A Antibody (4H4) - H00011320-M02 from Novus Biologicals

Prices	$359.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	4H4

MGAT4A Antibody - NBP1-81809 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: MGAT4A Antibody [NBP1-81809] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10. Lane 2: MOLT-4

MGAT4A Antibody (8C5) - H00011320-M01 from Novus Biologicals

Prices	$359.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	8C5

Western Blot: MGAT4A Antibody (8C5) [H00011320-M01] - MGAT4A monoclonal antibody (M01), clone 8C5. Analysis of MGAT4A expression in HepG2.

Anti-MGAT4A antibody produced in rabbit - HPA007608 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-MGAT4A: <B>Cat. No. HPA007608</B>: Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in islet cells.

Monoclonal Anti-MGAT4A, (C-terminal) antibody produced in mouse - SAB1404929 from Sigma-Aldrich

Prices	$347.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	8C5

<B>Immunoblotting</B><BR/>Monoclonal Anti-MGAT4A: <B>Cat. No. SAB1404929</B>: Antibody concentration: 1-5 μg/mL. Specific band of ~61.5 kDa using HepG2 lysate.

MGAT4A-Antibody-monoclonal-M02 - AT2856a from Abgent, a WuXi AppTec company

Prices	$315.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	4H4

Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .

MGAT4A-Antibody-monoclonal-M01 - AT2855a from Abgent, a WuXi AppTec company

Prices	$315.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	8C5

MGAT4A antibody [C1C3] - GTX119640 from GeneTex

Prices	$119.00
Sizes	25 μl
Host	Rabbit
Clonality	Polyclonal

Anti-MGAT4A antibody [C1C3] used in ICC/IF. GTX119640

MGAT4A antibody (FITC) - orb189940 from Biorbyt

Prices	$315.00
Sizes	100 μg
Host	Rabbit
Clonality	Polyclonal

MGAT4A Antibody - abx037290 from Abbexa

Host	Rabbit
Clonality	Polyclonal

MGAT4A antibody - 25109-1-AP from Acris Antibodies

Prices	$270.00
Sizes	150 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry of paraffin-embedded human small intestine tissue slide using 25109-1-AP( MGAT4A Antibody) at dilution of 1:50 (under 40x lens)

MGAT4A antibody - H00011320-M01 from Acris Antibodies

Prices	$360.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	8C5

MGAT4A monoclonal antibody (M01), clone 8C5. Western Blot analysis of MGAT4A expression in HepG2 ( Cat # L019V1 ).

MGAT4A antibody - H00011320-M02 from Acris Antibodies

Prices	$360.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	4H4

MGAT4A monoclonal antibody (M02), clone 4H4 Western Blot analysis of MGAT4A expression in Jurkat ( Cat # L017V1 ).

Mouse Anti-Human MGAT4A - 101-10994 from RayBiotech

Host	Mouse

MGAT4A antibody - 25109-1-AP from Proteintech Group

Prices	$279.00
Sizes	con: 43 μg/150μl
Host	Rabbit
Clonality	Polyclonal

HeLa cells were subjected to SDS PAGE followed by western blot with 25109-1-AP( MGAT4A Antibody) at dilution of 1:1000

MGAT4A Antibody - 40012 from Signalway Antibody

Prices	$390.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

MGAT4A Antibody - E306935 from Enogene

Prices	$275.00
Sizes	100ug/200ul

MGAT4A, Monoclonal Antibody - MBS649089 from MyBioSource

Prices	$580.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	4H4

Anti-MGAT4A (aa 360-527) polyclonal antibody - DPABH-02125 from Creative Diagnostics

Host	Rabbit
Clonality	Polyclonal

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