NKIRAS2

Gene Symbol	NKIRAS2
Entrez Gene	28511
Alt Symbol	KBRAS2, kappaB-Ras2
Species	Human
Gene Type	protein-coding
Description	NFKB inhibitor interacting Ras-like 2
Other Description	I-kappa-B-interacting Ras-like protein 2\|NF-kappa-B inhibitor-interacting Ras-like protein 2\|NFKB inhibitor interacting Ras-like protein 2\|kappa B-Ras protein 2
Swissprots	B4DNM3 B3KNN0 Q9NSX1 Q6PK52 A6NCZ5 Q96KC7 Q9NYR9
Accessions	ABC40741 EAW60790 EAW60791 EAW60792 EAW60793 EAW60794 Q9NYR9 AF229840 AAF34999 AK027265 BAB55006 AK054571 BAG51392 AK297975 BAG60285 AL137682 CAB70873 BC007316 BC007450 AAH07450 BC009059 BC063498 AAH63498 BG717103 DA509824 DA607452 DQ893233 ABM84159 DQ896563 ABM87562 XM_005257251 XP_005257308 XM_011524680 XP_011522982 XM_011524681 XP_011522983 XM_011524682 XP_011522984 NM_001001349 NP_001001349 NM_001144927 NP_001138399 NM_001144928 NP_001138400 NM_001144929 NP_001138401 NM_017595 NP_060065
Function	Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF- kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000250}.
Tissue Specificity	Widely expressed. {ECO:0000269\|PubMed:10657303}.

κB-Ras2 (C-16) - sc-10528 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Anti-NKIRAS2 antibody - ab57303 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

NKIRAS2 antibody (ab57303) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human tonsil.

Anti-NKIRAS2 antibody - ab129577 from Abcam

Prices	$370.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Anti-NKIRAS2 antibody (ab129577) at 1/100 dilution + U937 cell line lysates at 35 µgdeveloped using the ECL technique

Anti-NKIRAS2 Antibody (aa36-64, AP) - LS-C246607 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-NKIRAS2 Antibody (aa36-64, APC) - LS-C246608 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-NKIRAS2 Antibody (aa36-64, Biotin) - LS-C246609 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-NKIRAS2 Antibody (aa36-64, FITC) - LS-C246610 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-NKIRAS2 Antibody (aa36-64, PE) - LS-C246613 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-NKIRAS2 Antibody (C-Terminus) - LS-C81856 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-NKIRAS2 Antibody (aa110-159) - LS-C81855 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-NKIRAS2 Antibody (C-Terminus) - LS-C19462 from LifeSpan Bioscience

Prices	$325.00, $890.00
Sizes	100 µg, 500 µg
Host	Rabbit
Clonality	Polyclonal

Western blot of KappaB ras2 in RAW264.7 cell lysate with KappaB ras1 antibody at 1 ug/ml in the (A) absence and (B) presence of blocking peptide.

Anti-NKIRAS2 Antibody (aa36-64, Azide-free, HRP) - LS-C248918 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-NKIRAS2 Antibody (aa1-192, Azide-free) - LS-C327692 from LifeSpan Bioscience

Host	Mouse
Clonality	Monoclonal

Anti-NKIRAS2 Antibody (aa36-64) - LS-C164890 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

NKIRAS2 Antibody western blot of U937 cell line lysates (35 ug/lane). The NKIRAS2 antibody detected the NKIRAS2 protein (arrow).

Anti-NKIRAS2 Antibody (aa35-64) - LS-C323350 from LifeSpan Bioscience

Prices	$345.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-NKIRAS2 Antibody (clone 2G9) - LS-C133732 from LifeSpan Bioscience

Prices	$355.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	2G9

Immunoperoxidase of monoclonal antibody to NKIRAS2 on formalin-fixed paraffin-embedded human tonsil. [antibody concentration 3 ug/ml]

NKIRAS2 Antibody (2G9) - H00028511-M02 from Novus Biologicals

Prices	$359.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	2G9

Western Blot: NKIRAS2 Antibody (2G9) [H00028511-M02] - NKIRAS2 monoclonal antibody (M02), clone 2G9 Analysis of NKIRAS2 expression in HeLa.

NKIRAS2 Antibody - NBP1-31696 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: NKIRAS2 Antibody [NBP1-31696] - Sample (30 ug of whole cell lysate) A: 293T B: Hep G2 12% SDS PAGE; antibody diluted at 1:1000.

NKIRAS2 Antibody - NBP2-19545 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: NKIRAS2 Antibody [NBP2-19545] - Sample (30 ug of whole cell lysate) A: A549 12% SDS PAGE gel, diluted at 1:500.

NKIRAS2 Antibody - NBP1-58926 from Novus Biologicals

Prices	$139.00, $329.00
Sizes	20 µl, 100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: NKIRAS2 Antibody [NBP1-58926] - 721_B cell lysate, concentration 0.2-1 ug/ml.

NKIRAS2 Antibody - NBP1-58925 from Novus Biologicals

Prices	$139.00, $329.00
Sizes	20 µl, 100 µl
Host	Rabbit
Clonality	Polyclonal

Monoclonal Anti-NKIRAS2 antibody produced in mouse - WH0028511M2 from Sigma-Aldrich

Prices	$347.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	2G9

<B>Immunoblotting</B><BR/>Monoclonal Anti-NKIRAS2, <B>Cat. No. WH0028511M2</B> used at the antibody concentration: 1 ~ 5 μg/mL. Specific band of ~21.5 kDa using HeLa lysate.

Anti-NKIRAS2 (AB2) antibody produced in rabbit - AV54370 from Sigma-Aldrich

Prices	$347.50
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Cell Type: 721_B (<B>Cat. No. AV54370</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 1 μg/mL in cell type 721_B

Anti-NKIRAS2 (AB1) antibody produced in rabbit - AV54369 from Sigma-Aldrich

Prices	$347.50
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Cell Type: 721_B (<B>Cat. No. AV54369</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 1 μg/mL in cell type 721_B

Anti-KappaB ras2 antibody produced in rabbit - SAB3500261 from Sigma-Aldrich

Prices	$348.50
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-KappaB ras2: <B>Cat. No. SAB3500261</B>: Western blot analysis of KappaB ras2 in RAW264.7 cell lysate with KappaB ras1 antibody at 1 μg/mL in the (A) absence and (B) presence of blocking peptide.

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