Gene Symbol | NKIRAS2 |
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Entrez Gene | 28511 |
Alt Symbol | KBRAS2, kappaB-Ras2 |
Species | Human |
Gene Type | protein-coding |
Description | NFKB inhibitor interacting Ras-like 2 |
Other Description | I-kappa-B-interacting Ras-like protein 2|NF-kappa-B inhibitor-interacting Ras-like protein 2|NFKB inhibitor interacting Ras-like protein 2|kappa B-Ras protein 2 |
Swissprots | B4DNM3 B3KNN0 Q9NSX1 Q6PK52 A6NCZ5 Q96KC7 Q9NYR9 |
Accessions | ABC40741 EAW60790 EAW60791 EAW60792 EAW60793 EAW60794 Q9NYR9 AF229840 AAF34999 AK027265 BAB55006 AK054571 BAG51392 AK297975 BAG60285 AL137682 CAB70873 BC007316 BC007450 AAH07450 BC009059 BC063498 AAH63498 BG717103 DA509824 DA607452 DQ893233 ABM84159 DQ896563 ABM87562 XM_005257251 XP_005257308 XM_011524680 XP_011522982 XM_011524681 XP_011522983 XM_011524682 XP_011522984 NM_001001349 NP_001001349 NM_001144927 NP_001138399 NM_001144928 NP_001138400 NM_001144929 NP_001138401 NM_017595 NP_060065 |
Function | Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF- kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:10657303}. |
Human NKIRAS2 full length protein - ab124599 from Abcam
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NKIRAS2 Antibody Blocking Peptide - LS-E4249 from LifeSpan Bioscience
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NKIRAS2 Antibody Blocking Peptide - LS-E19564 from LifeSpan Bioscience
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NKIRAS2 Antibody Blocking Peptide - LS-E19563 from LifeSpan Bioscience
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NKIRAS2 Antibody Blocking Peptide - LS-E29977 from LifeSpan Bioscience
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NKIRAS2 Recombinant Protein - H00028511-P01 from Novus Biologicals
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NKIRAS2 Peptide - NBP1-76454PEP from Novus Biologicals
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Recombinant Human NKIRAS2 Protein - NBP1-99008 from Novus Biologicals
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NKIRAS2-Antibody-Center-Blocking-Peptide - BP16523c from Abgent, a WuXi AppTec company
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Human NKIRAS2 protein - orb168929 from Biorbyt
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NKIRAS2 Blocking Peptide - 33R-4460 from Fitzgerald
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NKIRAS2 Blocking Peptide - 33R-9632 from Fitzgerald
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NKIRAS2 protein (His tag) - 80R-2259 from Fitzgerald
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NKIRAS2 (1-191, His-tag) - AR50343PU-N from Acris Antibodies
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NKIRAS2 (1-191, His-tag) - AR50343PU-S from Acris Antibodies
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NKIRAS2 - H00028511-P01-10 from Acris Antibodies
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NKIRAS2 - H00028511-P01-25 from Acris Antibodies
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NKIRAS2 Control Peptide - AP30477CP-N from Acris Antibodies
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NKIRAS2, 1-191aa, Human, His tag, E.coli - 01-P1519 from ARP American Research Products
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KappaB ras2 Peptide - 2495P from ProSci
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NKIRAS2 fusion protein - ag0221 from Proteintech Group
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Recombinant Human NKIRAS2, His-tagged - NKIRAS2-27758TH from Creative Biomart
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Recombinant Human NFKB Inhibitor Interacting Ras-Like 2, His-tagged - NKIRAS2-5596H from Creative Biomart
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Recombinant Human NKIRAS2, His-tagged - NKIRAS2-15859H from Creative Biomart
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Recombinant Human NF-kappa-B inhibitor-interacting Ras-like protein 2(NKIRAS2) - CSB-YP873696HU CSB-EP873696HU CSB-BP873696HU CSB-MP873696HU from Cusabio
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