LIME1

Gene Symbol LIME1
Entrez Gene 54923
Alt Symbol LIME, dJ583P15.4
Species Human
Gene Type protein-coding
Description Lck interacting transmembrane adaptor 1
Other Description lck-interacting membrane protein|lck-interacting molecule|lck-interacting transmembrane adapter 1
Swissprots Q6XYB3 Q9H400 E1P5K6 E1P5K5 Q9NX69 Q5JWJ2
Accessions EAW75213 EAW75214 EAW75215 EAW75216 EAW75217 EAW75218 EAW75219 Q9H400 AI763397 AK000413 BAA91148 AK054722 AY203957 AAP34480 BC017016 AAH17016 BI911934 BP368475 NM_001305654 NP_001292583 NM_001305655 NP_001292584 NM_017806 NP_060276
Function Involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and TCR (T-cell antigen receptor)-mediated T- cell signaling in T-cells. In absence of TCR signaling, may be involved in CD4-mediated inhibition of T-cell activation. Couples activation of these receptors and their associated kinases with distal intracellular events such as calcium mobilization or MAPK activation through the recruitment of PLCG2, GRB2, GRAP2, and other signaling molecules. {ECO:0000269|PubMed:14610046}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:14610044, ECO:0000269|PubMed:14610046}; Single-pass type III membrane protein {ECO:0000269|PubMed:14610044, ECO:0000269|PubMed:14610046}. Note=Present in lipid rafts. Recruited to the immunological synapse upon conjugation of T-cell with antigen-presenting cell.
Tissue Specificity Expressed in peripheral blood lymphocytes, lymphoid tissues, and liver. Present in T-cells and plasma cells, and in various hematopoietic cell lines (at protein level). {ECO:0000269|PubMed:14610044, ECO:0000269|PubMed:14610046, ECO:0000269|PubMed:16160011}.

LIME (N-14) - sc-48581 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LIME (N-14): sc-48581. Western blot analysis of LIME expression in non-transfected: sc-110760 (A) and human LIME transfected: sc-112792 (B) 293 whole cell lysates.

LIME (D-6) - sc-166817 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
LIME (D-6): sc-166817. Western blot analysis of LIME expression in non-transfected: sc-110760 (A) and human LIME transfected: sc-112792 (B) 293 whole cell lysates.

LIME (E-1) - sc-166818 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
LIME (E-1): sc-166818. Western blot analysis of LIME expression in non-transfected: sc-110760 (A) and human LIME transfected: sc-112792 (B) 293 whole cell lysates.

LIME (M-14) - sc-48580 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LIME (M-14): sc-48580. Western blot analysis of LIME expression in non-transfected: sc-110760 (A) and human LIME transfected: sc-112792 (B) 293 whole cell lysates.

LIME (K-16) - sc-48579 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LIME (K-16): sc-48579. Western blot analysis of LIME expression in non-transfected: sc-110760 (A) and human LIME transfected: sc-112792 (B) 293 whole cell lysates.

LIME (A-7) - sc-365195 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
LIME (A-7): sc-365195. Western blot analysis of LIME expression in non-transfected: sc-110760 (A) and human LIME transfected: sc-112792 (B) 293 whole cell lysates.

LIME (FL-295) - sc-134595 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
LIME (FL-295): sc-134595. Western blot analysis of LIME expression in non-transfected: sc-110760 (A) and human LIME transfected: sc-112792 (B) 293 whole cell lysates.

LIME (H-8) - sc-376536 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
LIME (H-8): sc-376536. Western blot analysis of LIME expression in non-transfected: sc-110760 (A) and human LIME transfected: sc-112792 (B) 293 whole cell lysates.

LIME (FL-269) - sc-134596 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
LIME (FL-269): sc-134596. Western blot analysis of LIME expression in non-transfected: sc-110760 (A) and human LIME transfected: sc-112792 (B) 293 whole cell lysates.

LIME (C-15) - sc-48578 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LIME (C-15): sc-48578. Western blot analysis of LIME expression in non-transfected: sc-110760 (A) and human LIME transfected: sc-112792 (B) 293 whole cell lysates.

Anti-LIME antibody - ab14945 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LIME antibody - ab110094 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab110094, at 10µg/ml, staining LIME in formalin-fixed, paraffin-embedded Human Spleen tissue by Immunohistochemistry.

Anti-LIME antibody - ab123308 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-LIME antibody (ab123308) at 1/100 dilution + CEM cell line lysates at 35 µg

Anti-LIME antibody [EPR14713] - ab188871 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14713
Immunohistochemical analysis of paraffin-embedded Human mammary gland infiltrating duct carcinoma tissue labeling LIME with ab188871 at 1/2000 dilution followed by pre-diluted HRP Polymer for Rabbit IgG secondary antibody and counter-stained with Hematoxylin.

Anti-LIME antibody [LIME-06] (Phycoerythrin) - ab64678 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone LIME-06

Anti-LIME antibody [LIME-10] - ab14987 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone LIME-10

Anti-LIME1 / LIME Antibody (aa258-269) - LS-C20175 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Staining (1 ug/ml) of Mouse Heart lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by chemiluminescence.

Anti-LIME1 / LIME Antibody (aa281-296, clone LIME-10) - LS-C130416 from LifeSpan Bioscience

Prices $495.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone LIME-10

Anti-LIME1 / LIME Antibody - LS-C202772 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LIME1 / LIME Antibody (aa141-295, clone LIME-06) - LS-C204151 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone LIME-06

Anti-LIME1 / LIME Antibody (aa281-296, clone LIME-10) - LS-C204122 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone LIME-10

Anti-LIME1 / LIME Antibody (aa141-295) - LS-C204201 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LIME1 / LIME Antibody (aa190-219, APC) - LS-C237132 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LIME1 / LIME Antibody (aa190-219, AP) - LS-C237133 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LIME1 / LIME Antibody (aa190-219, FITC) - LS-C237134 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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