LIME1

Gene Symbol	LIME1
Entrez Gene	54923
Alt Symbol	LIME, dJ583P15.4
Species	Human
Gene Type	protein-coding
Description	Lck interacting transmembrane adaptor 1
Other Description	lck-interacting membrane protein|lck-interacting molecule|lck-interacting transmembrane adapter 1
Swissprots	Q6XYB3 Q9H400 E1P5K6 E1P5K5 Q9NX69 Q5JWJ2
Accessions	EAW75213 EAW75214 EAW75215 EAW75216 EAW75217 EAW75218 EAW75219 Q9H400 AI763397 AK000413 BAA91148 AK054722 AY203957 AAP34480 BC017016 AAH17016 BI911934 BP368475 NM_001305654 NP_001292583 NM_001305655 NP_001292584 NM_017806 NP_060276
Function	Involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and TCR (T-cell antigen receptor)-mediated T- cell signaling in T-cells. In absence of TCR signaling, may be involved in CD4-mediated inhibition of T-cell activation. Couples activation of these receptors and their associated kinases with distal intracellular events such as calcium mobilization or MAPK activation through the recruitment of PLCG2, GRB2, GRAP2, and other signaling molecules. {ECO:0000269|PubMed:14610046}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:14610044, ECO:0000269|PubMed:14610046}; Single-pass type III membrane protein {ECO:0000269|PubMed:14610044, ECO:0000269|PubMed:14610046}. Note=Present in lipid rafts. Recruited to the immunological synapse upon conjugation of T-cell with antigen-presenting cell.
Tissue Specificity	Expressed in peripheral blood lymphocytes, lymphoid tissues, and liver. Present in T-cells and plasma cells, and in various hematopoietic cell lines (at protein level). {ECO:0000269|PubMed:14610044, ECO:0000269|PubMed:14610046, ECO:0000269|PubMed:16160011}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human LIME full length protein - ab162894 from Abcam Category Protein Source Wheat germ Species Human

Human LIME protein fragment - ab176038 from Abcam Category Protein Source E. coli Species Human

LIME1 / LIME Antibody Blocking Peptide - LS-E3108 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LIME1 / LIME Antibody Blocking Peptide - LS-E25731 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LIME1 / LIME Antibody Blocking Peptide - LS-E25087 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LIME Recombinant Protein - H00054923-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human LIME Protein - NBP2-23181 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

LIME1-Antibody-C-term-Blocking-Peptide - BP14247b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

LIME1 protein (His tag) - 80R-3539 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

LIME1 (28-295, His-tag) - AR51227PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

LIME1 (28-295, His-tag) - AR51227PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

LIME1 - H00054923-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

LIME1 - H00054923-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

LIME1, 28-295aa, Human, His tag, E.coli - 01-P2406 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

Recombinant Human LIME1 - LIME1-957H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Human Lck-interacting transmembrane adapter 1(LIME1) - CSB-YP884463HU CSB-EP884463HU CSB-BP884463HU CSB-MP884463HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

This product has been discontinued. Please see note. - ATGP2406 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 20 µg, 100 µg, 500 µg

Lck Interacting Transmembrane Adaptor 1 Protein (Recombinant) - abx261198 from Abbexa Category Protein

Lck Interacting Molecule, Peptide - MBS658124 from MyBioSource Category Peptide Prices $340.00 Sizes 100 µg Species Mouse, Rat

LIME1 Peptide, Human - M34GP08716H from Creative Peptides Category Peptide Source Synthetic. Species Human

Human LIME1 protein - orb259948 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

LIME1 - PAT-82405-1 from Nordic BioSite Category Protein Species Human

LIME1 - PAT-82405-2 from Nordic BioSite Category Protein Species Human

Lck Interacting Transmembrane Adaptor 1, Human Recombinant - 228-21860-1 from RayBiotech Category Protein Species Human

Lck Interacting Transmembrane Adaptor 1, Recombinant Protein - MBS146550 from MyBioSource Category Protein Prices $140.00, $205.00, $2,665.00 Sizes 5 µg, 20 µg, 1 mg Source E Coli

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