LIME1

Gene Symbol	LIME1
Entrez Gene	54923
Alt Symbol	LIME, dJ583P15.4
Species	Human
Gene Type	protein-coding
Description	Lck interacting transmembrane adaptor 1
Other Description	lck-interacting membrane protein|lck-interacting molecule|lck-interacting transmembrane adapter 1
Swissprots	Q6XYB3 Q9H400 E1P5K6 E1P5K5 Q9NX69 Q5JWJ2
Accessions	EAW75213 EAW75214 EAW75215 EAW75216 EAW75217 EAW75218 EAW75219 Q9H400 AI763397 AK000413 BAA91148 AK054722 AY203957 AAP34480 BC017016 AAH17016 BI911934 BP368475 NM_001305654 NP_001292583 NM_001305655 NP_001292584 NM_017806 NP_060276
Function	Involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and TCR (T-cell antigen receptor)-mediated T- cell signaling in T-cells. In absence of TCR signaling, may be involved in CD4-mediated inhibition of T-cell activation. Couples activation of these receptors and their associated kinases with distal intracellular events such as calcium mobilization or MAPK activation through the recruitment of PLCG2, GRB2, GRAP2, and other signaling molecules. {ECO:0000269|PubMed:14610046}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:14610044, ECO:0000269|PubMed:14610046}; Single-pass type III membrane protein {ECO:0000269|PubMed:14610044, ECO:0000269|PubMed:14610046}. Note=Present in lipid rafts. Recruited to the immunological synapse upon conjugation of T-cell with antigen-presenting cell.
Tissue Specificity	Expressed in peripheral blood lymphocytes, lymphoid tissues, and liver. Present in T-cells and plasma cells, and in various hematopoietic cell lines (at protein level). {ECO:0000269|PubMed:14610044, ECO:0000269|PubMed:14610046, ECO:0000269|PubMed:16160011}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

LIME1 293T Cell Transient Overexpression Lysate(Denatured) - H00054923-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

LIME1 overexpression lysate - LY413516 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

LIME1 293 Cell Lysate - 406532 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

LIME Overexpression Lysate (Denatured) - H00054923-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

LIME Overexpression Lysate (Native) - NBL1-12535 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

LIME (h): 293 Lysate - sc-112792 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

LIME1 Over-expression Lysate Product - GWB-77A5C0 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Panoply™ Human LIME1 Knockdown Stable Cell Line - CSC-DC008716 from Creative biogene Category Cell Line Species Human

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