| Gene Symbol |
LARP6
|
| Entrez Gene |
55323
|
| Alt Symbol |
ACHN
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
La ribonucleoprotein domain family, member 6
|
| Other Description |
acheron|death-associated LA motif protein|la-related protein 6
|
| Swissprots |
Q5XKE4 Q9NUR0 Q8N3N2 Q9BRS8
|
| Accessions |
EAW77860 EAW77861 Q9BRS8 AF443828 AAN76710 AF443829 AAN76711 AI376944 AK002058 BAA92061 AK130092 AL833876 CAD38733 BC006082 AAH06082 BC009446 AAH09446 BC014018 AAH14018 BC039153 AAH39153 BI913258 DA715263 DN992782 NM_001286679 NP_001273608 NM_018357 NP_060827 NM_197958 NP_932062
|
| Function |
Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5' UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9. {ECO:0000269|PubMed:20603131, ECO:0000269|PubMed:21746880, ECO:0000269|PubMed:22190748}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:17383118}. Nucleus {ECO:0000269|PubMed:17383118}. Note=Shuttles between the nucleus and the cytoplasm.
|
| Tissue Specificity |
Expressed in numerous tissues. {ECO:0000269|PubMed:17383118}.
|