Gene Symbol | LARP6 |
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Entrez Gene | 55323 |
Alt Symbol | ACHN |
Species | Human |
Gene Type | protein-coding |
Description | La ribonucleoprotein domain family, member 6 |
Other Description | acheron|death-associated LA motif protein|la-related protein 6 |
Swissprots | Q5XKE4 Q9NUR0 Q8N3N2 Q9BRS8 |
Accessions | EAW77860 EAW77861 Q9BRS8 AF443828 AAN76710 AF443829 AAN76711 AI376944 AK002058 BAA92061 AK130092 AL833876 CAD38733 BC006082 AAH06082 BC009446 AAH09446 BC014018 AAH14018 BC039153 AAH39153 BI913258 DA715263 DN992782 NM_001286679 NP_001273608 NM_018357 NP_060827 NM_197958 NP_932062 |
Function | Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5' UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9. {ECO:0000269|PubMed:20603131, ECO:0000269|PubMed:21746880, ECO:0000269|PubMed:22190748}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:17383118}. Nucleus {ECO:0000269|PubMed:17383118}. Note=Shuttles between the nucleus and the cytoplasm. |
Tissue Specificity | Expressed in numerous tissues. {ECO:0000269|PubMed:17383118}. |
Human LARP6 full length protein - ab163063 from Abcam
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LARP6 / ACHN Antibody Blocking Peptide - LS-E533 from LifeSpan Bioscience
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LARP6 / ACHN Antibody Blocking Peptide - LS-E15001 from LifeSpan Bioscience
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Recombinant Human LARP6 Protein - H00055323-P01 from Novus Biologicals
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LARP6-Antibody-N-term-Blocking-peptide - BP10830a from Abgent, a WuXi AppTec company
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LARP6 Blocking Peptide - 33R-6082 from Fitzgerald
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LARP6 - H00055323-P01 from Acris Antibodies
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LARP6 fusion protein - ag13056 from Proteintech Group
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Recombinant Human La-related protein 6(LARP6) - CSB-YP887112HU CSB-EP887112HU CSB-BP887112HU CSB-MP887112HU from Cusabio
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LARP6 (transcript variant 2) - TP315460 from Acris Antibodies
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LARP6 Recombinant Protein Antigen - NBP1-89277PEP from Novus Biologicals
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LARP6 Peptide, Human - M34GP08552H from Creative Peptides
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LARP6 fusion protein - Ag24354 from Proteintech Group
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LARP6 Recombinant Protein Antigen - NBP2-55021PEP from Novus Biologicals
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La-related protein 6 (LARP6), Recombinant Protein - MBS1283776 from MyBioSource
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