Gene Symbol | LARP6 |
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Entrez Gene | 55323 |
Alt Symbol | ACHN |
Species | Human |
Gene Type | protein-coding |
Description | La ribonucleoprotein domain family, member 6 |
Other Description | acheron|death-associated LA motif protein|la-related protein 6 |
Swissprots | Q5XKE4 Q9NUR0 Q8N3N2 Q9BRS8 |
Accessions | EAW77860 EAW77861 Q9BRS8 AF443828 AAN76710 AF443829 AAN76711 AI376944 AK002058 BAA92061 AK130092 AL833876 CAD38733 BC006082 AAH06082 BC009446 AAH09446 BC014018 AAH14018 BC039153 AAH39153 BI913258 DA715263 DN992782 NM_001286679 NP_001273608 NM_018357 NP_060827 NM_197958 NP_932062 |
Function | Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5' UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9. {ECO:0000269|PubMed:20603131, ECO:0000269|PubMed:21746880, ECO:0000269|PubMed:22190748}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:17383118}. Nucleus {ECO:0000269|PubMed:17383118}. Note=Shuttles between the nucleus and the cytoplasm. |
Tissue Specificity | Expressed in numerous tissues. {ECO:0000269|PubMed:17383118}. |
Anti-LARP6 antibody - ab94640 from Abcam
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Anti-LARP6 antibody - ab107201 from Abcam
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Anti-LARP6 / ACHN Antibody (aa10-39, APC) - LS-C237018 from LifeSpan Bioscience
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Anti-LARP6 / ACHN Antibody (aa10-39, AP) - LS-C237017 from LifeSpan Bioscience
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Anti-LARP6 / ACHN Antibody (aa10-39, FITC) - LS-C237021 from LifeSpan Bioscience
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Anti-LARP6 / ACHN Antibody (aa10-39, PE) - LS-C237022 from LifeSpan Bioscience
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Anti-LARP6 / ACHN Antibody (aa10-39, Biotin) - LS-C237019 from LifeSpan Bioscience
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Anti-LARP6 / ACHN Antibody (aa10-39, Azide-free, HRP) - LS-C248687 from LifeSpan Bioscience
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Anti-LARP6 / ACHN Antibody - LS-C308715 from LifeSpan Bioscience
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Anti-LARP6 / ACHN Antibody (aa10-39) - LS-C329759 from LifeSpan Bioscience
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Anti-LARP6 / ACHN Antibody - LS-C311328 from LifeSpan Bioscience
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Anti-LARP6 / ACHN Antibody (C-Terminus) - LS-C110582 from LifeSpan Bioscience
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Anti-LARP6 / ACHN Antibody (aa7-35) - LS-C165687 from LifeSpan Bioscience
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LARP6 Antibody - H00055323-B01P from Novus Biologicals
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LARP6 Antibody - NBP1-57460 from Novus Biologicals
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LARP6 Antibody - NBP1-89277 from Novus Biologicals
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LARP6 Antibody - H00055323-D01 from Novus Biologicals
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Anti-LARP6 antibody produced in rabbit - SAB2104561 from Sigma-Aldrich
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Anti-LARP6 antibody produced in mouse - SAB1407657 from Sigma-Aldrich
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LARP6 antibody - middle region (ARP40912_P050) - ARP40912_P050 from Aviva Systems Biology
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LARP6 Antibody - C-terminal region (ARP74618_P050) - ARP74618_P050 from Aviva Systems Biology
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LARP6 Antibody - N-terminal region (OAAB00846) - OAAB00846 from Aviva Systems Biology
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LARP6-Antibody-N-term - AP10830a from Abgent, a WuXi AppTec company
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LARP6 antibody, Internal - GTX47282 from GeneTex
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LARP6 antibody - 70R-4880 from Fitzgerald
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