LARP6

Gene Symbol	LARP6
Entrez Gene	55323
Alt Symbol	ACHN
Species	Human
Gene Type	protein-coding
Description	La ribonucleoprotein domain family, member 6
Other Description	acheron|death-associated LA motif protein|la-related protein 6
Swissprots	Q5XKE4 Q9NUR0 Q8N3N2 Q9BRS8
Accessions	EAW77860 EAW77861 Q9BRS8 AF443828 AAN76710 AF443829 AAN76711 AI376944 AK002058 BAA92061 AK130092 AL833876 CAD38733 BC006082 AAH06082 BC009446 AAH09446 BC014018 AAH14018 BC039153 AAH39153 BI913258 DA715263 DN992782 NM_001286679 NP_001273608 NM_018357 NP_060827 NM_197958 NP_932062
Function	Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5' UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9. {ECO:0000269|PubMed:20603131, ECO:0000269|PubMed:21746880, ECO:0000269|PubMed:22190748}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:17383118}. Nucleus {ECO:0000269|PubMed:17383118}. Note=Shuttles between the nucleus and the cytoplasm.
Tissue Specificity	Expressed in numerous tissues. {ECO:0000269|PubMed:17383118}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

LARP6 CRISPR/Cas9 KO Plasmid (h) - sc-412519 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

LARP6 HDR Plasmid (h) - sc-412519-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

LARP6 Double Nickase Plasmid (h) - sc-412519-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

LARP6 Double Nickase Plasmid (h2) - sc-412519-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

LARP6 CRISPR Activation Plasmid (h) - sc-412519-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

LARP6 CRISPR Activation Plasmid (h2) - sc-412519-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

LARP6 Lentiviral Activation Particles (h) - sc-412519-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

LARP6 Lentiviral Activation Particles (h2) - sc-412519-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

LARP6 siRNA (h) - sc-90245 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

LARP6 shRNA Plasmid (h) - sc-90245-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

LARP6 shRNA (h) Lentiviral Particles - sc-90245-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

LARP6 RNAi - H00055323-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU067351 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN11554 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11554 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04002 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr04002

LARP6 siRNA (Human) - CRJ0655 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

LARP6 RNAi - H00055323-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

shRNA set against Human LARP6 (NM_197958.1) - SHH328539 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human LARP6(NM_197958.1) - SHH142535 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human LARP6(NM_018357.2) - SHH142553 from Creative biogene Category siRNA Species Reactivities Human

Human LARP6 siRNA - orb271156 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

LARP6 shRNA Plasmid (Human) - CHJ0655 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

LARP6 miRNA 3'UTR clone - MiUTR1H-05576 from Creative biogene Species Reactivities Human

LARP6 miRNA 3'UTR clone - MiUTR1H-05577 from Creative biogene Species Reactivities Human

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