ADHFE1

Gene Symbol	ADHFE1
Entrez Gene	137872
Alt Symbol	ADH8, HMFT2263, HOT
Species	Human
Gene Type	protein-coding
Description	alcohol dehydrogenase, iron containing, 1
Other Description	Fe-containing alcohol dehydrogenase 1|alcohol dehydrogenase 8|alcohol dehydrogenase iron-containing protein 1|hydroxyacid-oxoacid transhydrogenase, mitochondrial
Swissprots	Q6P2B6 Q96MF9 B4DTJ8 Q68CI7 Q49A19 Q8IWW8
Accessions	EAW86901 EAW86902 EAW86903 EAW86904 EAW86905 EAW86906 EAW86907 Q8IWW8 AB075879 BAD38661 AK056992 BAB71335 AK293530 BAG57012 AK294114 BAG57448 AK300243 BAG62010 AK300881 BAG62523 AY033237 AAK44223 BC047492 BC064634 AAH64634 BC110290 BE241883 BG698892 BQ182872 CB157325 NM_144650 NP_653251
Function	Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2- hydroxyglutarate (D-2-HG). D,L-3-hydroxyisobutyrate and L-3- hydroxybutyrate (L-3-OHB) are also substrates for HOT with 10-fold lower activities. {ECO:0000269|PubMed:16435184}.
Subcellular Location	Mitochondrion {ECO:0000250}.
Tissue Specificity	Only expressed in adult liver. {ECO:0000269|PubMed:12592711}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ADHFE1 full length protein - ab165408 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human ADHFE1 peptide - ab100853 from Abcam Category Peptide Prices $176.00 Sizes 100 µg Species Human

Human ADHFE1 protein fragment - ab165409 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

ADHFE1 Antibody Blocking Peptide - LS-E18989 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ADHFE1 Protein - H00137872-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human ADHFE1 Protein - H00137872-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ADHFE1 Blocking Peptide - 33R-7987 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ADHFE1 / HMFT2263 - H00137872-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ADHFE1 / HMFT2263 - H00137872-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ADHFE1 / HMFT2263 - H00137872-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ADHFE1 / HMFT2263 - H00137872-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ADHFE1 fusion protein - Ag6803 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

ADHFE1 fusion protein - ag6382 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human ADHFE1, His-tagged - ADHFE1-9422H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Hydroxyacid-oxoacid transhydrogenase, mitochondrial(ADHFE1) ,p - CSB-YP811615HU CSB-EP811615HU CSB-BP811615HU CSB-MP811615HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ADHFE1 Recombinant Protein Antigen - NBP1-83530PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ADHFE1-Antibody-Center-Blocking-Peptide - BP9062c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ADHFE1 Peptide, Human - M34GP00305H from Creative Peptides Category Peptide Source Synthetic. Species Human

Hydroxyacid-oxoacid transhydrogenase, mitochondrial (ADHFE1), partial, Recombinant Protein - MBS1476442 from MyBioSource Category Protein Prices $1,715.00, $1,870.00, $2,020.00, $2,135.00, $2,335.00, $2,365.00, $2,670.00, $2,930.00, $3,380.00, $4,220.00 Sizes 50 µg (Baculovirus), 500 µg (E-Coli), 500 µg (Yeast), 100 µg (Baculovirus), 1 mg (E-Coli), 50 µg (Mammalian-Cell), 1 mg (Yeast), 100 µg (Mammalian-Cell), 500 µg (Baculovirus), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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