ADHFE1

Gene Symbol ADHFE1
Entrez Gene 137872
Alt Symbol ADH8, HMFT2263, HOT
Species Human
Gene Type protein-coding
Description alcohol dehydrogenase, iron containing, 1
Other Description Fe-containing alcohol dehydrogenase 1|alcohol dehydrogenase 8|alcohol dehydrogenase iron-containing protein 1|hydroxyacid-oxoacid transhydrogenase, mitochondrial
Swissprots Q6P2B6 Q96MF9 B4DTJ8 Q68CI7 Q49A19 Q8IWW8
Accessions EAW86901 EAW86902 EAW86903 EAW86904 EAW86905 EAW86906 EAW86907 Q8IWW8 AB075879 BAD38661 AK056992 BAB71335 AK293530 BAG57012 AK294114 BAG57448 AK300243 BAG62010 AK300881 BAG62523 AY033237 AAK44223 BC047492 BC064634 AAH64634 BC110290 BE241883 BG698892 BQ182872 CB157325 NM_144650 NP_653251
Function Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2- hydroxyglutarate (D-2-HG). D,L-3-hydroxyisobutyrate and L-3- hydroxybutyrate (L-3-OHB) are also substrates for HOT with 10-fold lower activities. {ECO:0000269|PubMed:16435184}.
Subcellular Location Mitochondrion {ECO:0000250}.
Tissue Specificity Only expressed in adult liver. {ECO:0000269|PubMed:12592711}.

ADH8 CRISPR/Cas9 KO Plasmid (h) - sc-406475 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADH8 HDR Plasmid (h) - sc-406475-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADH8 Double Nickase Plasmid (h) - sc-406475-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADH8 Double Nickase Plasmid (h2) - sc-406475-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADH8 CRISPR Activation Plasmid (h) - sc-406475-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADH8 CRISPR Activation Plasmid (h2) - sc-406475-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADH8 Lentiviral Activation Particles (h) - sc-406475-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADH8 Lentiviral Activation Particles (h2) - sc-406475-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADH8 siRNA (h) - sc-77632 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ADH8 shRNA Plasmid (h) - sc-77632-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ADH8 shRNA (h) Lentiviral Particles - sc-77632-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ADHFE1 RNAi - H00137872-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU038611 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2880 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2880 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04315 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04315

ADHFE1 siRNA (Human) - CRJ5206 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ADHFE1 - MBS8208551 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ADHFE1 (NM_144650.2) - SHH232422 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human ADHFE1(NM_144650.2) - SHG042605 from Creative biogene

Category siRNA
Species Reactivities Human

ADHFE1 shRNA Plasmid (Human) - CHJ5206 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ADHFE1 miRNA 3'UTR clone - MiUTR1H-00197 from Creative biogene

Species Reactivities Human
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