Gene Symbol | KHDRBS3 |
---|---|
Entrez Gene | 10656 |
Alt Symbol | Etle, SALP, SLM-2, SLM2, T-STAR, TSTAR, etoile |
Species | Human |
Gene Type | protein-coding |
Description | KH domain containing, RNA binding, signal transduction associated 3 |
Other Description | KH domain-containing, RNA-binding, signal transduction-associated protein 3|RNA-binding protein T-Star|Sam68-like phosphotyrosine protein, T-STAR|sam68-like mammalian protein 2 |
Swissprots | Q9UPA8 Q6NUL8 O75525 |
Accessions | CCQ43363 EAW92182 O75525 AF051321 AAC99294 AF051322 AAC99295 AF069681 AAC24857 BC032606 AAH32606 BC068536 AAH68536 BX537666 CB155439 DQ890886 ABM81812 DQ894041 ABM84967 XM_005250757 XP_005250814 XM_005250758 XP_005250815 XM_011516796 XP_011515098 XM_011516797 XP_011515099 XM_011516798 XP_011515100 XM_011516799 XP_011515101 XR_242372 XR_242374 XR_928287 NM_006558 NP_006549 |
Function | RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. May play a role as a negative regulator of cell growth. Inhibits cell proliferation. Involved in splice site selection of vascular endothelial growth factor. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA- binding abilities are down-regulated by tyrosine kinase PTK6. Involved in post-transcriptional regulation of HIV-1 gene expression. Binds preferentially to the 5'-[AU]UAAA-3' motif in vitro. {ECO:0000269|PubMed:10564820, ECO:0000269|PubMed:11741900, ECO:0000269|PubMed:15901763}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:10332027, ECO:0000269|PubMed:15901763}. Note=Localized in a compartment adjacent to the nucleolus, but distinct from the peri-nucleolar one. |
Tissue Specificity | Ubiquitous with higher expression in testis, skeletal muscle and brain. Expressed in the kidney only in podocytes, the glomerular epithelial cells of the kidney. Strongly expressed after meiosis. {ECO:0000269|PubMed:10077576, ECO:0000269|PubMed:10332027, ECO:0000269|PubMed:10564820}. |
SLM-2 (E-9) - sc-398664 from Santa Cruz Biotechnology
|
||||||||
SLM-2 (F-3) - sc-374461 from Santa Cruz Biotechnology
|
||||||||
SLM-2 (M-20) - sc-9475 from Santa Cruz Biotechnology
|
||||||||
SLM-2 (S-15) - sc-9474 from Santa Cruz Biotechnology
|
||||||||
Anti-KHDRBS3 antibody - ab68515 from Abcam
|
||||||||
Anti-KHDRBS3 antibody - ab81545 from Abcam
|
||||||||
Anti-KHDRBS3 antibody - N-terminal - ab138759 from Abcam
|
||||||||
Anti-KHDRBS3 / SLM2 Antibody (N-Terminus) - LS-C145022 from LifeSpan Bioscience
|
||||||||
Anti-KHDRBS3 / SLM2 Antibody (aa18-47, AP) - LS-C261071 from LifeSpan Bioscience
|
||||||||
Anti-KHDRBS3 / SLM2 Antibody (aa18-47, APC) - LS-C261072 from LifeSpan Bioscience
|
||||||||
Anti-KHDRBS3 / SLM2 Antibody (aa18-47, Biotin) - LS-C261073 from LifeSpan Bioscience
|
||||||||
Anti-KHDRBS3 / SLM2 Antibody (aa18-47, FITC) - LS-C261074 from LifeSpan Bioscience
|
||||||||
Anti-KHDRBS3 / SLM2 Antibody (aa18-47, Azide-free, HRP) - LS-C261075 from LifeSpan Bioscience
|
||||||||
Anti-KHDRBS3 / SLM2 Antibody (aa18-47, PE) - LS-C261076 from LifeSpan Bioscience
|
||||||||
Anti-KHDRBS3 / SLM2 Antibody (aa175-225) - LS-C286152 from LifeSpan Bioscience
|
||||||||
Anti-KHDRBS3 / SLM2 Antibody (N-Terminus) - LS-C110551 from LifeSpan Bioscience
|
||||||||
Anti-KHDRBS3 / SLM2 Antibody (aa1-50) - LS-C289890 from LifeSpan Bioscience
|
||||||||
Anti-KHDRBS3 / SLM2 Antibody (C-Terminus) - LS-C30360 from LifeSpan Bioscience
|
||||||||
Anti-KHDRBS3 / SLM2 Antibody (aa18-47) - LS-C322433 from LifeSpan Bioscience
|
||||||||
Anti-KHDRBS3 / SLM2 Antibody (aa18-47) - LS-C159987 from LifeSpan Bioscience
|
||||||||
Anti-KHDRBS3 / SLM2 Antibody - LS-C346116 from LifeSpan Bioscience
|
||||||||
KHDRBS3 Antibody - NBP1-57104 from Novus Biologicals
|
||||||||
KHDRBS3 Antibody - NBP1-84774 from Novus Biologicals
|
||||||||
KHDRBS3 Antibody - NBP1-84773 from Novus Biologicals
|
||||||||
KHDRBS3 Antibody - NBP1-21324 from Novus Biologicals
|