Gene Symbol | KHDRBS3 |
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Entrez Gene | 10656 |
Alt Symbol | Etle, SALP, SLM-2, SLM2, T-STAR, TSTAR, etoile |
Species | Human |
Gene Type | protein-coding |
Description | KH domain containing, RNA binding, signal transduction associated 3 |
Other Description | KH domain-containing, RNA-binding, signal transduction-associated protein 3|RNA-binding protein T-Star|Sam68-like phosphotyrosine protein, T-STAR|sam68-like mammalian protein 2 |
Swissprots | Q9UPA8 Q6NUL8 O75525 |
Accessions | CCQ43363 EAW92182 O75525 AF051321 AAC99294 AF051322 AAC99295 AF069681 AAC24857 BC032606 AAH32606 BC068536 AAH68536 BX537666 CB155439 DQ890886 ABM81812 DQ894041 ABM84967 XM_005250757 XP_005250814 XM_005250758 XP_005250815 XM_011516796 XP_011515098 XM_011516797 XP_011515099 XM_011516798 XP_011515100 XM_011516799 XP_011515101 XR_242372 XR_242374 XR_928287 NM_006558 NP_006549 |
Function | RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. May play a role as a negative regulator of cell growth. Inhibits cell proliferation. Involved in splice site selection of vascular endothelial growth factor. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA- binding abilities are down-regulated by tyrosine kinase PTK6. Involved in post-transcriptional regulation of HIV-1 gene expression. Binds preferentially to the 5'-[AU]UAAA-3' motif in vitro. {ECO:0000269|PubMed:10564820, ECO:0000269|PubMed:11741900, ECO:0000269|PubMed:15901763}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:10332027, ECO:0000269|PubMed:15901763}. Note=Localized in a compartment adjacent to the nucleolus, but distinct from the peri-nucleolar one. |
Tissue Specificity | Ubiquitous with higher expression in testis, skeletal muscle and brain. Expressed in the kidney only in podocytes, the glomerular epithelial cells of the kidney. Strongly expressed after meiosis. {ECO:0000269|PubMed:10077576, ECO:0000269|PubMed:10332027, ECO:0000269|PubMed:10564820}. |
Human KHDRBS3 full length protein - ab161097 from Abcam
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KHDRBS3 / SLM2 Antibody Blocking Peptide - LS-E6350 from LifeSpan Bioscience
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KHDRBS3 / SLM2 Antibody Blocking Peptide - LS-E14889 from LifeSpan Bioscience
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KHDRBS3 / SLM2 Antibody Blocking Peptide - LS-E14890 from LifeSpan Bioscience
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Recombinant Human KHDRBS3 Protein - H00010656-P01 from Novus Biologicals
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KHDRBS3-Antibody-N-term-Blocking-Peptide - BP19054a from Abgent, a WuXi AppTec company
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KHDRBS3 Blocking Peptide - 33R-5904 from Fitzgerald
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KHDRBS3 Blocking Peptide - 33R-2680 from Fitzgerald
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KHDRBS3 - H00010656-P01-10 from Acris Antibodies
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KHDRBS3 - H00010656-P01-25 from Acris Antibodies
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KHDRBS3 fusion protein - ag4438 from Proteintech Group
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KHDRBS3 fusion protein - Ag5538 from Proteintech Group
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Recombinant Human KH domain-containing, RNA-binding, signal transduction-associa - CSB-YP012156HU CSB-EP012156HU CSB-BP012156HU CSB-MP012156HU from Cusabio
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KHDRBS3 Recombinant Protein Antigen - NBP1-84774PEP from Novus Biologicals
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KHDRBS3 Recombinant Protein Antigen - NBP1-84773PEP from Novus Biologicals
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KHDRBS3 Peptide, Human - M34GP08067H from Creative Peptides
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KH domain-containing, RNA-binding, signal transduction-associated protein 3 (KHDRBS3), Recombinant Protein - MBS1046230 from MyBioSource
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