KHDRBS3

Gene Symbol KHDRBS3
Entrez Gene 10656
Alt Symbol Etle, SALP, SLM-2, SLM2, T-STAR, TSTAR, etoile
Species Human
Gene Type protein-coding
Description KH domain containing, RNA binding, signal transduction associated 3
Other Description KH domain-containing, RNA-binding, signal transduction-associated protein 3|RNA-binding protein T-Star|Sam68-like phosphotyrosine protein, T-STAR|sam68-like mammalian protein 2
Swissprots Q9UPA8 Q6NUL8 O75525
Accessions CCQ43363 EAW92182 O75525 AF051321 AAC99294 AF051322 AAC99295 AF069681 AAC24857 BC032606 AAH32606 BC068536 AAH68536 BX537666 CB155439 DQ890886 ABM81812 DQ894041 ABM84967 XM_005250757 XP_005250814 XM_005250758 XP_005250815 XM_011516796 XP_011515098 XM_011516797 XP_011515099 XM_011516798 XP_011515100 XM_011516799 XP_011515101 XR_242372 XR_242374 XR_928287 NM_006558 NP_006549
Function RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. May play a role as a negative regulator of cell growth. Inhibits cell proliferation. Involved in splice site selection of vascular endothelial growth factor. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA- binding abilities are down-regulated by tyrosine kinase PTK6. Involved in post-transcriptional regulation of HIV-1 gene expression. Binds preferentially to the 5'-[AU]UAAA-3' motif in vitro. {ECO:0000269|PubMed:10564820, ECO:0000269|PubMed:11741900, ECO:0000269|PubMed:15901763}.
Subcellular Location Nucleus {ECO:0000269|PubMed:10332027, ECO:0000269|PubMed:15901763}. Note=Localized in a compartment adjacent to the nucleolus, but distinct from the peri-nucleolar one.
Tissue Specificity Ubiquitous with higher expression in testis, skeletal muscle and brain. Expressed in the kidney only in podocytes, the glomerular epithelial cells of the kidney. Strongly expressed after meiosis. {ECO:0000269|PubMed:10077576, ECO:0000269|PubMed:10332027, ECO:0000269|PubMed:10564820}.

SLM-2 CRISPR/Cas9 KO Plasmid (h) - sc-407141 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLM-2 HDR Plasmid (h) - sc-407141-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLM-2 Double Nickase Plasmid (h) - sc-407141-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLM-2 Double Nickase Plasmid (h2) - sc-407141-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLM-2 CRISPR Activation Plasmid (h) - sc-407141-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLM-2 CRISPR Activation Plasmid (h2) - sc-407141-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLM-2 Lentiviral Activation Particles (h) - sc-407141-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLM-2 Lentiviral Activation Particles (h2) - sc-407141-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SLM-2 siRNA (h) - sc-40922 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SLM-2 shRNA Plasmid (h) - sc-40922-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SLM-2 shRNA (h) Lentiviral Particles - sc-40922-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU077961 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN11049 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11049 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

KHDRBS3 siRNA (Human) - CRH7264 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human KHDRBS3 (NM_006558.1) - SHH324411 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human KHDRBS3(NM_006558.1) - SHL039846 from Creative biogene

Category siRNA
Species Reactivities Human

KHDRBS3 shRNA Plasmid (Human) - CHH7264 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

KHDRBS3 miRNA 3'UTR clone - MiUTR1H-05193 from Creative biogene

Species Reactivities Human
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