KHDRBS3

Gene Symbol	KHDRBS3
Entrez Gene	10656
Alt Symbol	Etle, SALP, SLM-2, SLM2, T-STAR, TSTAR, etoile
Species	Human
Gene Type	protein-coding
Description	KH domain containing, RNA binding, signal transduction associated 3
Other Description	KH domain-containing, RNA-binding, signal transduction-associated protein 3|RNA-binding protein T-Star|Sam68-like phosphotyrosine protein, T-STAR|sam68-like mammalian protein 2
Swissprots	Q9UPA8 Q6NUL8 O75525
Accessions	CCQ43363 EAW92182 O75525 AF051321 AAC99294 AF051322 AAC99295 AF069681 AAC24857 BC032606 AAH32606 BC068536 AAH68536 BX537666 CB155439 DQ890886 ABM81812 DQ894041 ABM84967 XM_005250757 XP_005250814 XM_005250758 XP_005250815 XM_011516796 XP_011515098 XM_011516797 XP_011515099 XM_011516798 XP_011515100 XM_011516799 XP_011515101 XR_242372 XR_242374 XR_928287 NM_006558 NP_006549
Function	RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. May play a role as a negative regulator of cell growth. Inhibits cell proliferation. Involved in splice site selection of vascular endothelial growth factor. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA- binding abilities are down-regulated by tyrosine kinase PTK6. Involved in post-transcriptional regulation of HIV-1 gene expression. Binds preferentially to the 5'-[AU]UAAA-3' motif in vitro. {ECO:0000269|PubMed:10564820, ECO:0000269|PubMed:11741900, ECO:0000269|PubMed:15901763}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:10332027, ECO:0000269|PubMed:15901763}. Note=Localized in a compartment adjacent to the nucleolus, but distinct from the peri-nucleolar one.
Tissue Specificity	Ubiquitous with higher expression in testis, skeletal muscle and brain. Expressed in the kidney only in podocytes, the glomerular epithelial cells of the kidney. Strongly expressed after meiosis. {ECO:0000269|PubMed:10077576, ECO:0000269|PubMed:10332027, ECO:0000269|PubMed:10564820}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

KHDRBS3-Over-expression-Lysate - LY13066a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

KHDRBS3 293T Cell Transient Overexpression Lysate(Denatured) - H00010656-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

KHDRBS3 overexpression lysate - LY416573 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

KHDRBS3 293 Cell Lysate - 407740 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

KHDRBS3 Overexpression Lysate (Native) - NBL1-12231 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

SLM-2 (h): 293T Lysate - sc-115279 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

SLM-2 (h3): 293T Lysate - sc-176558 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

KHDRBS3 Over-expression Lysate Product - GWB-C58074 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

KHDRBS3 Overexpression Lysate (Denatured) - H00010656-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Panoply™ Human KHDRBS3 Knockdown Stable Cell Line - CSC-DC008067 from Creative biogene Category Cell Line Species Human

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