MIEF2

Gene Symbol	MIEF2
Entrez Gene	125170
Alt Symbol	MID49, SMCR7
Species	Human
Gene Type	protein-coding
Description	mitochondrial elongation factor 2
Other Description	Smith-Magenis syndrome chromosomal region candidate gene 7 protein|Smith-Magenis syndrome chromosome region, candidate 7|mitochondrial dynamic protein MID49|mitochondrial dynamic protein of 49 kDa|mitochondrial dynamics protein MID49|mitochondrial dynamics protein of 49 kDa
Swissprots	Q96N07 Q96C03 Q6ZRD4 J3KPT3
Accessions	CCQ43835 EAW55651 EAW55652 Q96C03 AF467443 AAL78340 AK056165 BAB71108 AK128310 BAC87377 BC014973 AAH14973 BC035292 DB183618 JF432161 ADZ15378 NM_001144900 NP_001138372 NM_139162 NP_631901 NM_148886 NP_683684
Function	Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity. {ECO:0000269|PubMed:21508961, ECO:0000269|PubMed:23283981, ECO:0000269|PubMed:23530241, ECO:0000269|PubMed:23921378}.
Subcellular Location	Mitochondrion outer membrane {ECO:0000269|PubMed:21508961}; Single-pass membrane protein {ECO:0000269|PubMed:21508961}. Note=Colocalizes with DNM1L at mitochondrial membrane. Forms foci and rings around mitochondria.
Tissue Specificity	Expressed in all tissues tested with highest expression in heart and skeletal muscle. {ECO:0000269|PubMed:11997338}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SMCR7 full length protein - ab165233 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human SMCR7 Protein - H00125170-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SMCR7 - H00125170-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SMCR7 - H00125170-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SMCR7,MID49 fusion protein - Ag9503 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

SMCR7,MID49 fusion protein - Ag9531 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human SMCR7, His-tagged - SMCR7-2814H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Mitochondrial dynamic protein MID49(SMCR7) - CSB-YP842646HU CSB-EP842646HU CSB-BP842646HU CSB-MP842646HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SMCR7 (transcript variant 1) - TP318423 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

SMCR7 Recombinant Protein Antigen - NBP1-81165PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SMCR7 Peptide, Human - M34GP14744H from Creative Peptides Category Peptide Source Synthetic. Species Human

Mitochondrial dynamic protein MID49 (SMCR7), Recombinant Protein - MBS1463628 from MyBioSource Category Protein Prices $1,185.00, $1,185.00, $1,405.00, $1,405.00, $1,905.00, $1,905.00, $2,370.00, $2,370.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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