MIEF2

Gene Symbol MIEF2
Entrez Gene 125170
Alt Symbol MID49, SMCR7
Species Human
Gene Type protein-coding
Description mitochondrial elongation factor 2
Other Description Smith-Magenis syndrome chromosomal region candidate gene 7 protein|Smith-Magenis syndrome chromosome region, candidate 7|mitochondrial dynamic protein MID49|mitochondrial dynamic protein of 49 kDa|mitochondrial dynamics protein MID49|mitochondrial dynamics protein of 49 kDa
Swissprots Q96N07 Q96C03 Q6ZRD4 J3KPT3
Accessions CCQ43835 EAW55651 EAW55652 Q96C03 AF467443 AAL78340 AK056165 BAB71108 AK128310 BAC87377 BC014973 AAH14973 BC035292 DB183618 JF432161 ADZ15378 NM_001144900 NP_001138372 NM_139162 NP_631901 NM_148886 NP_683684
Function Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity. {ECO:0000269|PubMed:21508961, ECO:0000269|PubMed:23283981, ECO:0000269|PubMed:23530241, ECO:0000269|PubMed:23921378}.
Subcellular Location Mitochondrion outer membrane {ECO:0000269|PubMed:21508961}; Single-pass membrane protein {ECO:0000269|PubMed:21508961}. Note=Colocalizes with DNM1L at mitochondrial membrane. Forms foci and rings around mitochondria.
Tissue Specificity Expressed in all tissues tested with highest expression in heart and skeletal muscle. {ECO:0000269|PubMed:11997338}.

SMCR7 CRISPR/Cas9 KO Plasmid (h) - sc-406975 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMCR7 HDR Plasmid (h) - sc-406975-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMCR7 Double Nickase Plasmid (h) - sc-406975-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMCR7 Double Nickase Plasmid (h2) - sc-406975-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMCR7 CRISPR Activation Plasmid (h) - sc-406975-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMCR7 CRISPR Activation Plasmid (h2) - sc-406975-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMCR7 Lentiviral Activation Particles (h) - sc-406975-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMCR7 Lentiviral Activation Particles (h2) - sc-406975-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMCR7 siRNA (h) - sc-93868 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SMCR7 shRNA Plasmid (h) - sc-93868-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SMCR7 shRNA (h) Lentiviral Particles - sc-93868-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU081731 from Sigma-Aldrich

Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN19783 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19783 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07900 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07900

MIEF2 siRNA (Human) - CRJ4808 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SMCR7 CRISPR/Cas9 KO Plasmid (h2) - sc-406975-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMCR7 HDR Plasmid (h2) - sc-406975-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human SMCR7 (NM_148886.1) - SHH413340 from Creative biogene

Category siRNA
Species Reactivities Human

MIEF2 shRNA Plasmid (Human) - CHJ4808 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SMCR7 miRNA 3'UTR clone - MiUTR3H-16133 from Creative biogene

Species Reactivities Human

SMCR7 miRNA 3'UTR clone - MiUTR3H-16134 from Creative biogene

Species Reactivities Human

SMCR7 miRNA 3'UTR clone - MiUTR3H-16135 from Creative biogene

Species Reactivities Human
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