Gene Symbol | SEC13 |
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Entrez Gene | 6396 |
Alt Symbol | D3S1231E, SEC13L1, SEC13R, npp-20 |
Species | Human |
Gene Type | protein-coding |
Description | SEC13 homolog (S. cerevisiae) |
Other Description | SEC13-like 1 isoform|SEC13-like protein 1|SEC13-related protein|protein SEC13 homolog |
Swissprots | Q9BUG7 Q9BRM6 P55735 B4DXJ1 Q5BJF0 A8MV37 |
Accessions | EAW64077 EAW64078 P55735 AA682381 AB209554 BAD92791 AF052155 AK095629 AK223019 BAD96739 AK294662 BAG57832 AK301999 BAG63403 BC002634 AAH02634 BC006167 AAH06167 BC091506 AAH91506 BE621430 CN344033 DB564012 EF036494 ABO65080 EU789555 ACH92821 L09260 XM_005265378 XP_005265435 XM_005265379 XP_005265436 XM_006713288 XP_006713351 XM_011533996 XP_011532298 XM_011533997 XP_011532299 NM_001136026 NP_001129498 NM_001136232 NP_001129704 NM_001278946 NP_001265875 NM_030673 NP_109598 NM_183352 NP_899195 |
Function | Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles. As a component of the GATOR2 complex, inhibits GATOR1 complex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway. {ECO:0000269|PubMed:23723238, ECO:0000269|PubMed:8972206}. |
Subcellular Location | Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus, nuclear pore complex. Note=In interphase, localizes at both sides of the NPC. |
Top Pathways | Protein processing in endoplasmic reticulum, RNA transport |
SEC13 (F-6) - sc-514308 from Santa Cruz Biotechnology
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SEC13 (C-14) - sc-103195 from Santa Cruz Biotechnology
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SEC13 (H-242) - sc-368099 from Santa Cruz Biotechnology
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SEC13 (N-16) - sc-103196 from Santa Cruz Biotechnology
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SEC13 (S-13) - sc-103197 from Santa Cruz Biotechnology
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Anti-SEC13L1 antibody - ab107411 from Abcam
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Anti-SEC13L1 antibody - ab167310 from Abcam
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Anti-SEC13L1 antibody - C-terminal - ab199922 from Abcam
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Anti-SEC13 Antibody (aa270-320) - LS-C290626 from LifeSpan Bioscience
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Anti-SEC13 Antibody (aa72-100, AP) - LS-C217426 from LifeSpan Bioscience
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Anti-SEC13 Antibody (aa72-100, Biotin) - LS-C217427 from LifeSpan Bioscience
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Anti-SEC13 Antibody (aa72-100, APC) - LS-C217428 from LifeSpan Bioscience
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Anti-SEC13 Antibody (aa72-100, FITC) - LS-C217429 from LifeSpan Bioscience
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Anti-SEC13 Antibody (aa72-100, Azide-free, HRP) - LS-C217430 from LifeSpan Bioscience
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Anti-SEC13 Antibody (clone 1G7) - LS-C198175 from LifeSpan Bioscience
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Anti-SEC13 Antibody (aa72-100, PE) - LS-C217432 from LifeSpan Bioscience
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Anti-SEC13 Antibody (aa75-104) - LS-C324970 from LifeSpan Bioscience
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Anti-SEC13 Antibody (aa191-240) - LS-C205838 from LifeSpan Bioscience
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Anti-SEC13 Antibody (aa101-150) - LS-C206135 from LifeSpan Bioscience
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Anti-SEC13 Antibody (aa72-100) - LS-C168924 from LifeSpan Bioscience
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Anti-SEC13 Antibody (aa1-319) - LS-C185388 from LifeSpan Bioscience
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SEC13 Antibody - NBP1-92374 from Novus Biologicals
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SEC13 Antibody - NBP1-33291 from Novus Biologicals
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SEC13 Antibody - NBP2-20278 from Novus Biologicals
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SEC13 Antibody - H00006396-A01 from Novus Biologicals
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