Gene Symbol | SEC13 |
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Entrez Gene | 6396 |
Alt Symbol | D3S1231E, SEC13L1, SEC13R, npp-20 |
Species | Human |
Gene Type | protein-coding |
Description | SEC13 homolog (S. cerevisiae) |
Other Description | SEC13-like 1 isoform|SEC13-like protein 1|SEC13-related protein|protein SEC13 homolog |
Swissprots | Q9BUG7 Q9BRM6 P55735 B4DXJ1 Q5BJF0 A8MV37 |
Accessions | EAW64077 EAW64078 P55735 AA682381 AB209554 BAD92791 AF052155 AK095629 AK223019 BAD96739 AK294662 BAG57832 AK301999 BAG63403 BC002634 AAH02634 BC006167 AAH06167 BC091506 AAH91506 BE621430 CN344033 DB564012 EF036494 ABO65080 EU789555 ACH92821 L09260 XM_005265378 XP_005265435 XM_005265379 XP_005265436 XM_006713288 XP_006713351 XM_011533996 XP_011532298 XM_011533997 XP_011532299 NM_001136026 NP_001129498 NM_001136232 NP_001129704 NM_001278946 NP_001265875 NM_030673 NP_109598 NM_183352 NP_899195 |
Function | Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles. As a component of the GATOR2 complex, inhibits GATOR1 complex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway. {ECO:0000269|PubMed:23723238, ECO:0000269|PubMed:8972206}. |
Subcellular Location | Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus, nuclear pore complex. Note=In interphase, localizes at both sides of the NPC. |
Top Pathways | Protein processing in endoplasmic reticulum, RNA transport |
Human SEC13L1 full length protein - ab105635 from Abcam
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Human SEC13L1 full length protein - ab125173 from Abcam
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SEC13 Antibody Blocking Peptide - LS-E454 from LifeSpan Bioscience
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SEC13 Partial Recombinant Protein - H00006396-Q01 from Novus Biologicals
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SEC13 Recombinant Protein - H00006396-P01 from Novus Biologicals
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SEC13 Recombinant Protein - H00006396-P02 from Novus Biologicals
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Recombinant Human SEC13 Protein - NBP1-51076 from Novus Biologicals
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SEC13-Antibody-Center-Blocking-peptide - BP10738c from Abgent, a WuXi AppTec company
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SEC13 Protein (OPPA00189) - OPPA00189 from Aviva Systems Biology
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Human SEC13 protein - orb169268 from Biorbyt
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SEC13 protein (His tag) - 80R-1766 from Fitzgerald
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SEC13 (1-322, His-tag) - AR09948PU-L from Acris Antibodies
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SEC13 (1-322, His-tag) - AR09948PU-N from Acris Antibodies
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SEC13 - H00006396-P01-10 from Acris Antibodies
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SEC13 - H00006396-P01-25 from Acris Antibodies
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SEC13 - H00006396-P02 from Acris Antibodies
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SEC13 - H00006396-P02-10 from Acris Antibodies
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SEC13 - H00006396-P02-25 from Acris Antibodies
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SEC13 - H00006396-Q01-10 from Acris Antibodies
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SEC13 - H00006396-Q01-25 from Acris Antibodies
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SEC13, Human Recombinant - 228-12948-1 from RayBiotech
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Recombinant Human SEC13 - 228-12948-2 from RayBiotech
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Recombinant Human SEC13 - 228-12948-3 from RayBiotech
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SEC13, 1-322aa, Human, His tag, E.coli - 01-P1008 from ARP American Research Products
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SEC13 fusion protein - Ag7506 from Proteintech Group
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