Gene Symbol | SMTNL1 |
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Entrez Gene | 219537 |
Alt Symbol | CHASM |
Species | Human |
Gene Type | protein-coding |
Description | smoothelin-like 1 |
Other Description | calponin homology-associated smooth muscle protein|smoothelin-like protein 1 |
Swissprots | A8MU46 |
Accessions | A8MU46 BC172381 AAI72381 XM_005273819 XP_005273876 NM_001105565 NP_001099035 |
Function | Plays a role in the regulation of contractile properties of both striated and smooth muscles. When unphosphorylated, may inhibit myosin dephosphorylation. Phosphorylation at Ser-299 reduces this inhibitory activity (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm, myofibril {ECO:0000269|PubMed:18310078}. Cytoplasm, myofibril, sarcomere, I band {ECO:0000250}. Cytoplasm, myofibril, sarcomere, M line {ECO:0000250}. Nucleus {ECO:0000250}. Note=Colocalizes with MYH2. In its unphosphorylated state, localizes to the cytoplasm (By similarity). Phosphorylation at Ser-301 promotes translocation to the nucleus (By similarity). {ECO:0000250}. |
Tissue Specificity | Expressed in striated muscles, specifically in type 2a fibers (at protein level). {ECO:0000269|PubMed:18310078, ECO:0000269|PubMed:20634291}. |
SMTNL1 (B-7) - sc-390589 from Santa Cruz Biotechnology
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SMTNL1 (G-7) - sc-390369 from Santa Cruz Biotechnology
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SMTNL1 (P-12) - sc-162239 from Santa Cruz Biotechnology
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SMTNL1 (T-14) - sc-162240 from Santa Cruz Biotechnology
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Anti-SMTNL1 antibody - ab170398 from Abcam
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Anti-SMTNL1 antibody - ab122645 from Abcam
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Anti-SMTNL1 antibody - N-terminal - ab187011 from Abcam
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Anti-SMTNL1 Antibody (aa130-159, APC) - LS-C269723 from LifeSpan Bioscience
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Anti-SMTNL1 Antibody (aa130-159, Biotin) - LS-C269724 from LifeSpan Bioscience
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Anti-SMTNL1 Antibody (aa130-159, FITC) - LS-C269725 from LifeSpan Bioscience
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Anti-SMTNL1 Antibody (aa130-159, PE) - LS-C269728 from LifeSpan Bioscience
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Anti-SMTNL1 Antibody (aa130-159, Azide-free, HRP) - LS-C269726 from LifeSpan Bioscience
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Anti-SMTNL1 Antibody (aa137-167) - LS-C325213 from LifeSpan Bioscience
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Anti-SMTNL1 Antibody (aa82-131) - LS-C205860 from LifeSpan Bioscience
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Anti-SMTNL1 Antibody (aa130-159) - LS-C161328 from LifeSpan Bioscience
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Anti-SMTNL1 Antibody (aa130-159, AP) - LS-C269721 from LifeSpan Bioscience
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SMTNL1 Antibody - NBP1-90630 from Novus Biologicals
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SMTNL1 Antibody - N-terminal region (ARP66682_P050) - ARP66682_P050 from Aviva Systems Biology
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SMTNL1-Antibody-Center - AP11480c from Abgent, a WuXi AppTec company
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SMTNL1 Antibody - middle region (OAAB07724) - OAAB07724 from Aviva Systems Biology
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SMTNL1 antibody - 70R-21703 from Fitzgerald
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Smoothelin-Like 1 Antibody - abx115625 from Abbexa
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SMTNL1 (Center) antibody - AP53951PU-N from Acris Antibodies
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smoothelin-like 1 , Polyclonal Antibody - MBS712161 from MyBioSource
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SMTNL1, Polyclonal Antibody - MBS6011830 from MyBioSource
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