SMTNL1

Gene Symbol SMTNL1
Entrez Gene 219537
Alt Symbol CHASM
Species Human
Gene Type protein-coding
Description smoothelin-like 1
Other Description calponin homology-associated smooth muscle protein|smoothelin-like protein 1
Swissprots A8MU46
Accessions A8MU46 BC172381 AAI72381 XM_005273819 XP_005273876 NM_001105565 NP_001099035
Function Plays a role in the regulation of contractile properties of both striated and smooth muscles. When unphosphorylated, may inhibit myosin dephosphorylation. Phosphorylation at Ser-299 reduces this inhibitory activity (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm, myofibril {ECO:0000269|PubMed:18310078}. Cytoplasm, myofibril, sarcomere, I band {ECO:0000250}. Cytoplasm, myofibril, sarcomere, M line {ECO:0000250}. Nucleus {ECO:0000250}. Note=Colocalizes with MYH2. In its unphosphorylated state, localizes to the cytoplasm (By similarity). Phosphorylation at Ser-301 promotes translocation to the nucleus (By similarity). {ECO:0000250}.
Tissue Specificity Expressed in striated muscles, specifically in type 2a fibers (at protein level). {ECO:0000269|PubMed:18310078, ECO:0000269|PubMed:20634291}.

SMTNL1 CRISPR/Cas9 KO Plasmid (h) - sc-410379 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMTNL1 HDR Plasmid (h) - sc-410379-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMTNL1 Double Nickase Plasmid (h) - sc-410379-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMTNL1 Double Nickase Plasmid (h2) - sc-410379-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMTNL1 CRISPR Activation Plasmid (h) - sc-410379-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMTNL1 CRISPR Activation Plasmid (h2) - sc-410379-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMTNL1 Lentiviral Activation Particles (h) - sc-410379-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMTNL1 Lentiviral Activation Particles (h2) - sc-410379-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SMTNL1 siRNA (h) - sc-97014 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SMTNL1 shRNA Plasmid (h) - sc-97014-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SMTNL1 shRNA (h) Lentiviral Particles - sc-97014-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU231601 from Sigma-Aldrich

Category siRNA
Prices $140.00, $140.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19809 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19809 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

shRNA set against Human Smtnl1 (NM_001105565.2) - SHH413696 from Creative biogene

Category siRNA
Species Reactivities Human
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