| Gene Symbol | SMTNL1 |
|---|---|
| Entrez Gene | 219537 |
| Alt Symbol | CHASM |
| Species | Human |
| Gene Type | protein-coding |
| Description | smoothelin-like 1 |
| Other Description | calponin homology-associated smooth muscle protein|smoothelin-like protein 1 |
| Swissprots | A8MU46 |
| Accessions | A8MU46 BC172381 AAI72381 XM_005273819 XP_005273876 NM_001105565 NP_001099035 |
| Function | Plays a role in the regulation of contractile properties of both striated and smooth muscles. When unphosphorylated, may inhibit myosin dephosphorylation. Phosphorylation at Ser-299 reduces this inhibitory activity (By similarity). {ECO:0000250}. |
| Subcellular Location | Cytoplasm, myofibril {ECO:0000269|PubMed:18310078}. Cytoplasm, myofibril, sarcomere, I band {ECO:0000250}. Cytoplasm, myofibril, sarcomere, M line {ECO:0000250}. Nucleus {ECO:0000250}. Note=Colocalizes with MYH2. In its unphosphorylated state, localizes to the cytoplasm (By similarity). Phosphorylation at Ser-301 promotes translocation to the nucleus (By similarity). {ECO:0000250}. |
| Tissue Specificity | Expressed in striated muscles, specifically in type 2a fibers (at protein level). {ECO:0000269|PubMed:18310078, ECO:0000269|PubMed:20634291}. |
Smoothelin-like protein 1, SMTNL1, Human, ELISA Kit - E2278h from ARP American Research Products
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smoothelin-like 1, ELISA Kit - MBS9328016 from MyBioSource
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Human SMTNL1 ELISA Kit (Custom ELISA) - LS-F19661 from LifeSpan Bioscience
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Human SMTNL1 ELISA Kit - E035544 from Biobool
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SMTNL1 ELISA Kit (Human) (OKEH05186) - OKEH05186 from Aviva Systems Biology
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Smoothelin-like protein 1, ELISA Kit - MBS2882699 from MyBioSource
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