SMARCD3

Gene Symbol	SMARCD3
Entrez Gene	6604
Alt Symbol	BAF60C, CRACD3, Rsc6p
Species	Human
Gene Type	protein-coding
Description	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
Other Description	60 kDa BRG-1/Brm-associated factor subunit C|BRG1-associated factor 60C|SWI/SNF complex 60 kDa subunit C|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3|Swp73-like protein|chromatin remodeling complex BAF60C subunit|mammalian chromatin remodeling complex BRG1-associated factor 60C
Swissprots	Q6STE5 Q92926 Q2YD86 Q9BUH1 Q75MR8 D3DX10 Q75MJ2
Accessions	AAS00380 AAS02031 EAL24510 EAW54005 EAW54006 EAW54007 EAW54008 EAW54009 Q6STE5 AK127595 BAG54531 AK297876 BAH12684 AK309500 AK316173 BAH14544 AY450430 AAR88510 AY450431 AAR88511 BC002628 AAH02628 BC110350 AAI10351 BI598614 BX648385 U66619 AAC50697 XM_011516521 XP_011514823 XR_927517 XR_927518 XR_927519 NM_001003801 NP_001003801 NM_001003802 NP_001003802 NM_003078 NP_003069
Function	Plays a role in ATP dependent nucleosome remodeling by SMARCA4 containing complexes. Stimulates nuclear receptor mediated transcription. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron- specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post- mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent
Subcellular Location	Nucleus {ECO:0000269|PubMed:14701856}.
Tissue Specificity	Isoform 2 and isoform 1 are expressed in brain, heart, kidney, placenta, prostate, salivary gland, spleen, testis, thyroid, trachea and uterus. Isoform 1 is also expressed in skeletal muscle and adipose tissue.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SMARCD3 full length protein - ab152695 from Abcam Category Protein Source Wheat germ Species Human

Human SMARCD3 protein fragment - ab152696 from Abcam Category Protein Source Wheat germ Species Human

BAF60C / SMARCD3 Antibody Blocking Peptide - LS-E25144 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human SMARCD3 Protein - H00006604-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human SMARCD3 Protein - H00006604-P01 from Novus Biologicals Category Protein Prices $250.00 Sizes 2 µg Source Wheat Germ Species Human

Smarcd3 Blocking Peptide - 33R-2053 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SMARCD3 - H00006604-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

SMARCD3 - H00006604-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

SMARCD3 - H00006604-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

SMARCD3 fusion protein - ag19242 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

SMARCD3 fusion protein - Ag3896 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3(SMARCD3) - CSB-YP754358HU CSB-EP754358HU CSB-BP754358HU CSB-MP754358HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SMARCD3 (full length, N-term HIS tag, transcript variant 1) - TP760791 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

SMARCD3 Recombinant Protein Antigen - NBP2-39013PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SMARCD3-Blocking-Peptide-N-term - BP20613a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SMARCD3 Peptide, Human - M34GP14733H from Creative Peptides Category Peptide Source Synthetic. Species Human

SMARCD3 Recombinant Protein Antigen - NBP2-57036PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 (SMARCD3), Recombinant Protein - MBS1349974 from MyBioSource Category Protein Prices $1,265.00, $1,265.00, $1,485.00, $1,485.00, $2,070.00, $2,070.00, $2,535.00, $2,535.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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