ORC4

Gene Symbol	ORC4
Entrez Gene	5000
Alt Symbol	ORC4L, ORC4P
Species	Human
Gene Type	protein-coding
Description	origin recognition complex, subunit 4
Other Description	origin recognition complex subunit 4|origin recognition complex, subunit 4 homolog
Swissprots	O43929 B7Z3D0 Q96C42 B7Z5F1 D3DP86 F5H069
Accessions	AAS94326 AAX93051 AAY24232 EAX11555 EAX11556 EAX11557 EAX11558 EAX11559 EAX11560 O43929 AF022108 AAC01957 AF047598 AAC80282 AF132596 AAD22110 AK055257 AK128860 AK225092 AK291989 BAF84678 AK294878 BAH11910 AK295721 BAH12166 AK298862 BAH12887 AK299749 BAH13118 AV708885 BC005388 BC014847 AAH14847 BC016177 AAH16177 BI603609 BM468640 BM926755 BP277082 BP345092 BQ716497 BX423253 CD242597 DA120022 DA227202 DB558580 DC302315 DC317404 DC329505 DC365436 DC365653 DC399282 DC399552 EU446991 ABZ92520 XM_006712556 XP_006712619 XM_011511255 XP_011509557 NM_001190879 NP_001177808 NM_001190881 NP_001177810 NM_001190882 NP_001177811 NM_002552 NP_002543 NM_181741 NP_859525 NM_181742 NP_859526
Function	Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre- replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3. {ECO:0000269|PubMed:22427655}.
Subcellular Location	Nucleus.
Top Pathways	Cell cycle

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ORC4L peptide - ab23156 from Abcam Category Peptide Species Human

Human ORC4L protein fragment - ab114619 from Abcam Category Protein Source Wheat germ Species Human

ORC4L / ORC4 Antibody Blocking Peptide - LS-E25218 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ORC4L / ORC4 Antibody Blocking Peptide - LS-E21115 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ORC4L Protein - H00005000-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ORC4L blocking peptide - GTX89991-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

Human ORC4 protein - orb244423 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

ORC4L Blocking Peptide - 33R-9651 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ORC4L Peptide - AC21-0040-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

ORC4 - H00005000-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ORC4 - H00005000-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ORC4L Peptide - 46-102P from ProSci Category Peptide Species Human, Mouse

ORC4L fusion protein - ag3625 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human ORC4 - ORC4-30514TH from Creative Biomart Category Protein Source Wheat germ Species Human

Recombinant Human Origin recognition complex subunit 4(ORC4) - CSB-YP017234HU CSB-BP017234HU CSB-MP017234HU from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

Recombinant Human Origin recognition complex subunit 4 - CSB-EP017234HU from Cusabio Category Protein Source E.coli Species Human

BCA-1/BLC (CXCL13), human recombinant - 4001-20 from Biovision Category Protein Prices $180.00 Sizes 20 µg Source E. coli Species Human

ORC4 Protein - abx163913 from Abbexa Category Protein Species Human

ORC4 (transcript variant 2) - TP301587 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

ORC4 (transcript variant 3) - TP311713 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

ORC4 (transcript variant 1) - TP311723 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

ORC4L, Peptide - MBS426636 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Bovine

ORC4 Peptide, Human - M34GP11126H from Creative Peptides Category Peptide Source Synthetic. Species Human

ORC4 Recombinant Protein (OPCA01771) - OPCA01771 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

Recombinant Human Origin recognition complex subunit 4 - AP70609 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

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