ORC4

Gene Symbol ORC4
Entrez Gene 5000
Alt Symbol ORC4L, ORC4P
Species Human
Gene Type protein-coding
Description origin recognition complex, subunit 4
Other Description origin recognition complex subunit 4|origin recognition complex, subunit 4 homolog
Swissprots O43929 B7Z3D0 Q96C42 B7Z5F1 D3DP86 F5H069
Accessions AAS94326 AAX93051 AAY24232 EAX11555 EAX11556 EAX11557 EAX11558 EAX11559 EAX11560 O43929 AF022108 AAC01957 AF047598 AAC80282 AF132596 AAD22110 AK055257 AK128860 AK225092 AK291989 BAF84678 AK294878 BAH11910 AK295721 BAH12166 AK298862 BAH12887 AK299749 BAH13118 AV708885 BC005388 BC014847 AAH14847 BC016177 AAH16177 BI603609 BM468640 BM926755 BP277082 BP345092 BQ716497 BX423253 CD242597 DA120022 DA227202 DB558580 DC302315 DC317404 DC329505 DC365436 DC365653 DC399282 DC399552 EU446991 ABZ92520 XM_006712556 XP_006712619 XM_011511255 XP_011509557 NM_001190879 NP_001177808 NM_001190881 NP_001177810 NM_001190882 NP_001177811 NM_002552 NP_002543 NM_181741 NP_859525 NM_181742 NP_859526
Function Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre- replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3. {ECO:0000269|PubMed:22427655}.
Subcellular Location Nucleus.
Top Pathways Cell cycle

ORC4 (17) - sc-136331 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ORC4 (17): sc-136331. Western blot analysis of ORC4 expression in A-431 whole cell lysate.

ORC4 (H-2) - sc-398455 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ORC4 (H-2): sc-398455. Western blot analysis of ORC4 expression in non-transfected: sc-117752 (A) and human ORC4 transfected: sc-113520 (B) 293T whole cell lysates.

ORC4 (C-15) - sc-19726 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ORC4 (C-15): sc-19726. Western blot analysis of ORC4 expression in non-transfected: sc-117752 (A) and human ORC4 transfected: sc-113520 (B) 293T whole cell lysates.

ORC4 (D-8) - sc-393985 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ORC4 (D-8): sc-393985. Western blot analysis of ORC4 expression in A549 whole cell lysate.

ORC4 (L-15) - sc-19725 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ORC4 (L-15): sc-19725. Western blot analysis of ORC4 expression in non-transfected: sc-117752 (A) and human ORC4 transfected: sc-113520 (B) 293T whole cell lysates.

ORC4 (H-300) - sc-20634 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ORC4 (H-300): sc-20634. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.

Anti-ORC4L antibody - ab88999 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-ORC4L antibody (ab88999) at 1/500 dilution + Jurkat cell lysate at 50 µg

Anti-ORC4L antibody - C-terminal - ab154235 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-ORC4L antibody - C-terminal (ab154235) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

Anti-ORC4L / ORC4 Antibody - LS-C317859 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ORC4L / ORC4 Antibody (HRP) - LS-C317861 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ORC4L / ORC4 Antibody (FITC) - LS-C317862 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ORC4L / ORC4 Antibody (Biotin) - LS-C318964 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ORC4L / ORC4 Antibody (C-Terminus) - LS-C345829 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of ORC4 Antibody with human HeLa Whole Cell lysate.

Anti-ORC4L / ORC4 Antibody (aa323-372) - LS-C112125 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ORC4 / ORC4L antibody LS-C112125 Western blot of Fetal Liver lysate.

Anti-ORC4L / ORC4 Antibody (aa350-362) - LS-C55203 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (2 ug/ml) staining of Jurkat lysate (RIPA buffer, 1.4E5 cells per lane). Detected by Western blot of chemiluminescence.

Anti-ORC4L / ORC4 Antibody (clone 2A8) - LS-C197825 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2A8
Immunofluorescence of monoclonal antibody to ORC4L on HeLa cell . [antibody concentration 10 ug/ml]

ORC4L Antibody - H00005000-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: ORC4L Antibody [H00005000-B01] - ORC4L MaxPab polyclonal antibody. Western Blot analysis of ORC4L expression in Jurkat.

ORC4L Antibody - NBP1-31132 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ORC4L Antibody [NBP1-31132] - Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE ORC4L antibody, antibody diluted at 1:1000.

ORC4L Antibody - NB100-798 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: ORC4L Antibody [NB100-798] - Staining (0.5ug/ml) of Jurkat nuclear lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

ORC4L Antibody - NBP1-58167 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ORC4L Antibody [NBP1-58167] - Human Liver cell lysate, concentration 0.2-1 ug/ml.

ORC4L Antibody - NBP2-19633 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ORC4L Antibody (2A8) - H00005000-M05 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2A8
Immunocytochemistry/Immunofluorescence: ORC4L Antibody (2A8) [H00005000-M05] - Analysis of monoclonal antibody to ORC4L on HeLa cell. Antibody concentration 10 ug/ml

ORC4L Antibody - H00005000-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: ORC4L Antibody [H00005000-D01P] - Analysis of ORC4L expression in transfected 293T cell line by ORC4L polyclonal antibody.Lane 1: ORC4L transfected lysate(50.40 KDa).Lane 2: Non-transfected lysate.

ORC4L Antibody - H00005000-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: ORC4L Antibody [H00005000-B01P] - Analysis of ORC4L expression in Jurkat.

ORC4L Antibody - H00005000-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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