ORC4

Gene Symbol ORC4
Entrez Gene 5000
Alt Symbol ORC4L, ORC4P
Species Human
Gene Type protein-coding
Description origin recognition complex, subunit 4
Other Description origin recognition complex subunit 4|origin recognition complex, subunit 4 homolog
Swissprots O43929 B7Z3D0 Q96C42 B7Z5F1 D3DP86 F5H069
Accessions AAS94326 AAX93051 AAY24232 EAX11555 EAX11556 EAX11557 EAX11558 EAX11559 EAX11560 O43929 AF022108 AAC01957 AF047598 AAC80282 AF132596 AAD22110 AK055257 AK128860 AK225092 AK291989 BAF84678 AK294878 BAH11910 AK295721 BAH12166 AK298862 BAH12887 AK299749 BAH13118 AV708885 BC005388 BC014847 AAH14847 BC016177 AAH16177 BI603609 BM468640 BM926755 BP277082 BP345092 BQ716497 BX423253 CD242597 DA120022 DA227202 DB558580 DC302315 DC317404 DC329505 DC365436 DC365653 DC399282 DC399552 EU446991 ABZ92520 XM_006712556 XP_006712619 XM_011511255 XP_011509557 NM_001190879 NP_001177808 NM_001190881 NP_001177810 NM_001190882 NP_001177811 NM_002552 NP_002543 NM_181741 NP_859525 NM_181742 NP_859526
Function Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre- replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3. {ECO:0000269|PubMed:22427655}.
Subcellular Location Nucleus.
Top Pathways Cell cycle

ORC4 CRISPR/Cas9 KO Plasmid (h) - sc-403634 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ORC4 HDR Plasmid (h) - sc-403634-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ORC4 Double Nickase Plasmid (h) - sc-403634-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ORC4 Double Nickase Plasmid (h2) - sc-403634-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ORC4 CRISPR Activation Plasmid (h) - sc-403634-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ORC4 CRISPR Activation Plasmid (h2) - sc-403634-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ORC4 Lentiviral Activation Particles (h) - sc-403634-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ORC4 Lentiviral Activation Particles (h2) - sc-403634-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ORC4 siRNA (h) - sc-38157 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ORC4 shRNA Plasmid (h) - sc-38157-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ORC4 shRNA (h) Lentiviral Particles - sc-38157-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ORC4L RNAi - H00005000-R05 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

ORC4L RNAi - H00005000-R04 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

ORC4L RNAi - H00005000-R06 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU064641 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16146 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16146 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09046 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09046

ORC4 siRNA (Human) - CRH3318 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ORC4 (NM_181742.3) - SHH368444 from Creative biogene

Category siRNA
Species Reactivities Human

ORC4 shRNA Plasmid (Human) - CHH3318 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ORC4 miRNA 3'UTR clone - MiUTR3H-05602 from Creative biogene

Species Reactivities Human

ORC4 miRNA 3'UTR clone - MiUTR3H-05603 from Creative biogene

Species Reactivities Human

ORC4 miRNA 3'UTR clone - MiUTR3H-05604 from Creative biogene

Species Reactivities Human
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