| Gene Symbol | MED14 |
|---|---|
| Entrez Gene | 9282 |
| Alt Symbol | CRSP150, CRSP2, CSRP, CXorf4, DRIP150, EXLM1, RGR1, TRAP170 |
| Species | Human |
| Gene Type | protein-coding |
| Description | mediator complex subunit 14 |
| Other Description | ARC150|CRSP complex subunit 2|RGR1 homolog|activator-recruited cofactor 150 kDa component|cofactor required for Sp1 transcriptional activation, subunit 2 (150kD)|hRGR1|human homolog of yeast RGR1|mediator of RNA polymerase II transcription subunit 14|thyroid hormone receptor-associated protein complex 170 kDa component|thyroid hormone receptor-associated protein complex component TRAP170|transcriptional co-activator CRSP150|vitamin D receptor-interacting protein complex component DRIP150|vitamin D3 receptor-interacting protein complex 150 kDa component |
| Swissprots | Q9UNB3 Q4KMR7 O60244 |
| Accessions | BAA28627 EAW59419 EAW59420 O60244 AB006651 BAA28626 AF070563 AF104256 AAD12725 AF135802 AAD24360 AF304448 AAG22547 AJ012077 AK023368 AK293070 BAF85759 AK308871 BC098377 AAH98377 BC132672 AAI32673 BC132674 AAI32675 BC144231 HG518165 CDI06888 XM_005272701 XP_005272758 XM_011544000 XP_011542302 NM_004229 NP_004220 |
| Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. {ECO:0000269|PubMed:15340088, ECO:0000269|PubMed:15625066, ECO:0000269|PubMed:16595664}. |
| Subcellular Location | Nucleus {ECO:0000305}. |
| Tissue Specificity | Ubiquitous. |
Calcitonin receptor-stimulating peptide 2 (CRSP2), Human, ELISA Kit - E01C2077 from ARP American Research Products
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Mediator of RNA polymerase II transcription subunit 14 (MED14), Human, ELISA Kit - E01M0067 from ARP American Research Products
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Mediator of RNA polymerase II transcription subunit 14 (MED14), ELISA Kit - MBS7252800 from MyBioSource
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Mediator of RNA polymerase II transcription subunit 14 (MED14), ELISA Kit - MBS7252554 from MyBioSource
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Mediator of RNA polymerase II transcription subunit 14 (MED14), ELISA Kit - MBS7237983 from MyBioSource
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Mediator of RNA polymerase II transcription subunit 14 (MED14), ELISA Kit - MBS7229280 from MyBioSource
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Mediator of RNA polymerase II transcription subunit 14 (MED14), ELISA Kit - MBS7221357 from MyBioSource
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Mediator of RNA polymerase II transcription subunit 14 (MED14), ELISA Kit - MBS7211888 from MyBioSource
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Mediator of RNA polymerase II transcription subunit 14 (MED14), ELISA Kit - MBS7226247 from MyBioSource
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Mediator of RNA polymerase II transcription subunit 14 (MED14), ELISA Kit - MBS7245453 from MyBioSource
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Mediator of RNA polymerase II transcription subunit 14 (MED14), ELISA Kit - MBS7212964 from MyBioSource
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Mediator of RNA polymerase II transcription subunit 14 (MED14), ELISA Kit - MBS7220414 from MyBioSource
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Mediator of RNA polymerase II transcription subunit 14 (MED14), ELISA Kit - MBS7239870 from MyBioSource
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Human CRSP2 ELISA Kit - E005975 from Biobool
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Human MED14 ELISA Kit - E023924 from Biobool
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Human Mediator of RNA polymerase II transcription subunit 14 (MED14) ELISA Kit - AE33889HU from ARP American Research Products
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