DOCK4

Gene Symbol DOCK4
Entrez Gene 9732
Alt Symbol -
Species Human
Gene Type protein-coding
Description dedicator of cytokinesis 4
Other Description dedicator of cytokinesis protein 4
Swissprots O14584 Q8N1I0 Q8NB45 O94824
Accessions AAB83946 AAS07431 EAL24377 EAW83451 EAW83452 EAW83453 EAW83454 EAW83455 EAW83456 Q8N1I0 AB018259 BAA34436 AF085922 AK055497 AK091557 BAC03696 AK098050 BAC05221 AK294722 BAH11861 AK294820 BAH11895 AK309605 AY233380 AAO73565 BC117688 AAI17689 BC117689 AAI17690 BC117694 AAI17695 BM126591 BM545903 DA646980 XM_006716188 XP_006716251 XM_006716189 XP_006716252 XM_011516716 XP_011515018 XM_011516717 XP_011515019 NM_014705 NP_055520
Function Involved in regulation of adherens junction between cells. Plays a role in cell migration. Functions as a guanine nucleotide exchange factor (GEF), which activates Rap1 small GTPase by exchanging bound GDP for free GTP. {ECO:0000269|PubMed:12628187, ECO:0000269|PubMed:20679435}.
Subcellular Location Endomembrane system; Peripheral membrane protein. Cytoplasm, cytosol.
Tissue Specificity Widely expressed at low level. Highly expressed in skeletal muscle, prostate and ovary. {ECO:0000269|PubMed:12628187}.
Top Pathways Rap1 signaling pathway

DOCK 4 (C-15) - sc-70165 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DOCK 4 (C-15): sc-70165. Western blot analysis of DOCK 4 expression in rat prostate tissue extract.

DOCK 4 (K-18) - sc-70166 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

DOCK 4 (S-19) - sc-70168 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DOCK 4 (S-19): sc-70168. Western blot analysis of DOCK 4 expression in rat prostate tissue extract.

DOCK 4 (R6Y) - sc-100718 from Santa Cruz Biotechnology

Prices $295.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
DOCK 4 (R6Y): sc-100718. Western blot analysis of DOCK 4 expression in HeLa nuclear extract.

Anti-DOCK4 antibody - ab56743 from Abcam

Prices $384.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
DOCK4 antibody (ab56743) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human breast cancer.

Anti-DOCK4 antibody - ab85723 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human ovarian carcinoma tissue labelling DOCK4 with ab85723 at 1/200 (1µg/ml). Detection: DAB.

Anti-DOCK4 antibody - ab111876 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab111876 at 1/250 dilution staining DOCK4 in Formalin-fixed, Paraffin-embedded Human ovarian carcinoma tissue by Immunohistochemistry. Detection: DAB staining.

Anti-DOCK4 Antibody (aa1916-1966) - LS-C289016 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DOCK4 Antibody (aa1867-1967, Azide-free) - LS-C330412 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-DOCK4 Antibody (aa1725-1775) - LS-C289015 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human DOCK4 by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-DOCK4 used at a dilution of 1:200 (1 ug/ml). Detection: DAB.

Anti-DOCK4 Antibody (aa1725-1775) - LS-C286853 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human DOCK4 by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-DOCK4 used at a dilution of 1:250.

Anti-DOCK4 Antibody (clone 3E7) - LS-C105088 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3E7
Immunofluorescence of monoclonal antibody to DOCK4 on HeLa cell (antibody concentration 10 ug/ml).

DOCK4 Antibody (3E7) - H00009732-M01 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3E7

DOCK4 Antibody - NBP1-26648 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: DOCK4 Antibody [NBP1-26648] - Whole cell lysate from HeLa and 293T cells. DOCK4 was also immunoprecipitated by rabbit anti-DOCK4 antibody NBP1-26649.

DOCK4 Antibody (1B3) - H00009732-M03 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1B3
Western Blot: DOCK4 Antibody (1B3) [H00009732-M03] - DOCK4 monoclonal antibody (M03), clone 1B3. Western Blot analysis of DOCK4 expression in PC-12 ( Cat # L012V1 ).

DOCK4 Antibody - NBP1-26649 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunoprecipitation: DOCK4 Antibody [NBP1-26649] - Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit used for IP at 3 mcg/mg lysate.

DOCK4 Antibody - NBP1-71959 from Novus Biologicals

Host Rabbit
Clonality Polyclonal
Immunohistochemistry: DOCK4 Antibody [NBP1-71959]-FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-DOCK4 ) used at a dilution of 1:100.

DOCK4 Antibody (3E7) - H00009732-M01A from Novus Biologicals

Prices $349.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 3E7
Western Blot: DOCK4 Antibody (3E7) [H00009732-M01A] - DOCK4 monoclonal antibody (M01), clone 3E7 Western Blot analysis of DOCK4 expression in Hela NE ( Cat # L013V3 ).

DOCK4 Antibody - H00009732-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

DOCK4 Polyclonal Antibody - bs-12432R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DOCK4 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-12432R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DOCK4 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-12432R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DOCK4 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-12432R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DOCK4 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-12432R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DOCK4 Polyclonal Antibody, Cy3 Conjugated - bs-12432R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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