DOCK4

Gene Symbol	DOCK4
Entrez Gene	9732
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	dedicator of cytokinesis 4
Other Description	dedicator of cytokinesis protein 4
Swissprots	O14584 Q8N1I0 Q8NB45 O94824
Accessions	AAB83946 AAS07431 EAL24377 EAW83451 EAW83452 EAW83453 EAW83454 EAW83455 EAW83456 Q8N1I0 AB018259 BAA34436 AF085922 AK055497 AK091557 BAC03696 AK098050 BAC05221 AK294722 BAH11861 AK294820 BAH11895 AK309605 AY233380 AAO73565 BC117688 AAI17689 BC117689 AAI17690 BC117694 AAI17695 BM126591 BM545903 DA646980 XM_006716188 XP_006716251 XM_006716189 XP_006716252 XM_011516716 XP_011515018 XM_011516717 XP_011515019 NM_014705 NP_055520
Function	Involved in regulation of adherens junction between cells. Plays a role in cell migration. Functions as a guanine nucleotide exchange factor (GEF), which activates Rap1 small GTPase by exchanging bound GDP for free GTP. {ECO:0000269|PubMed:12628187, ECO:0000269|PubMed:20679435}.
Subcellular Location	Endomembrane system; Peripheral membrane protein. Cytoplasm, cytosol.
Tissue Specificity	Widely expressed at low level. Highly expressed in skeletal muscle, prostate and ovary. {ECO:0000269|PubMed:12628187}.
Top Pathways	Rap1 signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DOCK4 protein fragment - ab153015 from Abcam Category Protein Source Wheat germ Species Human

DOCK4 Partial Recombinant Protein - H00009732-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

DOCK4 - H00009732-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

DOCK4 - H00009732-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

DOCK4 fusion protein - Ag16516 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

DOCK4 fusion protein - Ag16498 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human DOCK4, GST-tagged - DOCK4-12119H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Dedicator Of Cytokinesis 4 (DOCK4) - RPG184Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Dedicator Of Cytokinesis 4 (DOCK4) - RPG184Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Dedicator of cytokinesis protein 4(DOCK4) ,partial - CSB-YP854021HU CSB-EP854021HU CSB-BP854021HU CSB-MP854021HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Dedicator Of Cytokinesis 4 Protein (Recombinant) - abx168105 from Abbexa Category Protein Source Human Species Human

DOCK4 Peptide, Human - M34GP04476H from Creative Peptides Category Peptide Source Synthetic. Species Human

DOCK4 fusion protein - Ag25965 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Dedicator Of Cytokinesis 4 (DOCK4) - RPU51889 from Biomatik Category Protein Prices $180.00, $369.00, $564.00, $672.40 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

DOCK4 Recombinant Protein (OPCD02780) - OPCD02780 from Aviva Systems Biology Category Protein Source E.coli Species Human

DOCK4 Recombinant Protein Antigen - NBP2-57555PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Dedicator Of Cytokinesis 4, Recombinant Protein - MBS2031627 from MyBioSource Category Protein Prices $175.00, $370.00, $575.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Human

Dedicator of cytokinesis protein 4 (DOCK4), partial, Recombinant Protein - MBS1465313 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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