DOCK4

Gene Symbol DOCK4
Entrez Gene 9732
Alt Symbol -
Species Human
Gene Type protein-coding
Description dedicator of cytokinesis 4
Other Description dedicator of cytokinesis protein 4
Swissprots O14584 Q8N1I0 Q8NB45 O94824
Accessions AAB83946 AAS07431 EAL24377 EAW83451 EAW83452 EAW83453 EAW83454 EAW83455 EAW83456 Q8N1I0 AB018259 BAA34436 AF085922 AK055497 AK091557 BAC03696 AK098050 BAC05221 AK294722 BAH11861 AK294820 BAH11895 AK309605 AY233380 AAO73565 BC117688 AAI17689 BC117689 AAI17690 BC117694 AAI17695 BM126591 BM545903 DA646980 XM_006716188 XP_006716251 XM_006716189 XP_006716252 XM_011516716 XP_011515018 XM_011516717 XP_011515019 NM_014705 NP_055520
Function Involved in regulation of adherens junction between cells. Plays a role in cell migration. Functions as a guanine nucleotide exchange factor (GEF), which activates Rap1 small GTPase by exchanging bound GDP for free GTP. {ECO:0000269|PubMed:12628187, ECO:0000269|PubMed:20679435}.
Subcellular Location Endomembrane system; Peripheral membrane protein. Cytoplasm, cytosol.
Tissue Specificity Widely expressed at low level. Highly expressed in skeletal muscle, prostate and ovary. {ECO:0000269|PubMed:12628187}.
Top Pathways Rap1 signaling pathway

DOCK 4 CRISPR/Cas9 KO Plasmid (h) - sc-405235 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DOCK 4 HDR Plasmid (h) - sc-405235-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DOCK 4 Double Nickase Plasmid (h) - sc-405235-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DOCK 4 Double Nickase Plasmid (h2) - sc-405235-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DOCK 4 CRISPR Activation Plasmid (h) - sc-405235-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DOCK 4 CRISPR Activation Plasmid (h2) - sc-405235-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DOCK 4 Lentiviral Activation Particles (h) - sc-405235-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DOCK 4 Lentiviral Activation Particles (h2) - sc-405235-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DOCK 4 siRNA (h) - sc-77170 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DOCK 4 shRNA Plasmid (h) - sc-77170-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DOCK 4 shRNA (h) Lentiviral Particles - sc-77170-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DOCK4 RNAi - H00009732-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU074981 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7420 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7420 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11129 from Sigma-Aldrich

Category miRNA

DOCK4 siRNA (Human) - CRH6500 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DOCK4 - MBS8222321 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human DOCK4 (NM_014705.3) - SHH280193 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human DOCK4(NM_014705.3) - SHH013241 from Creative biogene

Category siRNA
Species Reactivities Human

Human DOCK4 siRNA - orb267002 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DOCK4 shRNA Plasmid (Human) - CHH6500 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DOCK4 miRNA 3'UTR clone - MiUTR1H-02953 from Creative biogene

Species Reactivities Human
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