HERPUD1

Gene Symbol HERPUD1
Entrez Gene 9709
Alt Symbol HERP, Mif1, SUP
Species Human
Gene Type protein-coding
Description homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
Other Description MMS-inducible|homocysteine-inducible endoplasmic reticulum stress-inducible ubiquitin-like domain member 1 protein|homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein|methyl methanesulfonate (MMF)-inducible fragment protein 1
Swissprots Q96D92 O60644 Q15011 E9PGD1 Q6IAN8
Accessions BAB19010 EAW82892 EAW82893 EAW82894 Q15011 AB034989 BAB07891 AF055001 AAC09355 AF055003 AAC09357 AF217990 AAG17233 AK223233 BAD96953 AK291565 BAF84254 AK292088 BAF84777 AK302167 BAG63534 AK304800 BAG65550 BC000086 AAH00086 BC008320 AAH08320 BC009739 AAH09739 BC032673 AAH32673 BG685245 BI520043 CD358537 CR457116 CAG33397 D14695 BAA03521 DA581153 DQ837586 ABI18163 DQ891867 ABM82793 EU176642 ABW03443 XM_006721352 XP_006721415 NM_001010989 NP_001010989 NM_001272103 NP_001259032 NM_014685 NP_055500 NM_001010990
Function Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Could enhance presenilin-mediated beta-amyloid protein 40 generation. {ECO:0000269|PubMed:16289116}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:10922362}; Multi-pass membrane protein {ECO:0000269|PubMed:10922362}.
Tissue Specificity Widely expressed; in the brain, expression seems to be restricted to neurons and vascular smooth muscle cells. Present in activated microglia in senile plaques in the brain of patients with Alzheimer disease.
Top Pathways Protein processing in endoplasmic reticulum

HERP (H-59) - sc-98669 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
HERP (H-59): sc-98669. Western blot analysis of HERP expression in non-transfected: sc-117752 (A) and human HERP transfected: sc-171055 (B) 293T whole cell lysates.

HERP (L-13) - sc-69495 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HERP (L-13): sc-69495. Western blot analysis of HERP expression in mouse brain tissue extract.

HERP (S-18) - sc-69497 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HERP (S-18): sc-69497. Immunoperoxidase staining of formalin fixed, paraffin-embedded human skeletal muscle tissue showing cytoplasmic staining of myocytes.

HERP (19-Y) - sc-100721 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
HERP (19-Y): sc-100721. Western blot analysis of HERP expression in Hep G2 whole cell lysate.

Anti-HERPUD1 antibody - ab73669 from Abcam

Prices $380.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-HERPUD1 antibody (ab73669) at 1 µg/mlLane 1 : Colon (Mouse) Tissue Lysate Lane 2 : Colon (Rat) Tissue LysateLane 3 : Colon tissue lysate (Human) Tissue Lysate - adult normal tissue (ab30051)Lane 4 : Skeletal Muscle (Mouse) Tissue Lysate Lane 5 : Skeletal Muscle (Rat) Tissue Lysate Lane 6 : Skeletal Muscle (Human) Tissue Lysate - adult normal tissue (ab29330)Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutionPerformed under reducing conditions.

Anti-HERPUD1 antibody - ab155778 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-HERPUD1 antibody (ab155778) at 1/1000 dilution + Mouse brain whole cell lysate at 50 µg

Anti-HERPUD1 antibody - ab56742 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
HERPUD1 antibody (ab56742) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human tonsil.

Anti-HERPUD1 antibody - ab76766 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-HERPUD1 antibody - ab130723 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-HERPUD1 antibody (ab130723) at 1/100 dilution + HepG2 cell lysate at 35 µg/ml

Anti-HERPUD1 antibody [EPR9649] - ab150424 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9649
All lanes : Anti-HERPUD1 antibody [EPR9649] (ab150424) at 1/1000 dilutionLane 1 : BxPC-3 cell lysateLane 2 : HepG2 cell lysateLane 3 : SH-SY5Y cell lysateLane 4 : 293T cell lysateLysates/proteins at 10 µg per lane.

Anti-HERPUD1 / HERP Antibody (clone 2G7) - LS-C105087 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2G7
Western blot of HERPUD1 expression in transfected 293T cell line by HERPUD1 monoclonal antibody (M04), clone 2G7.

Anti-HERPUD1 / HERP Antibody (clone 1A2) - LS-C338324 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1A2
IHC of paraffin-embedded Human endometrium tissue using anti-HERPUD1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

Anti-HERPUD1 / HERP Antibody (C-Terminus) - LS-C144952 from LifeSpan Bioscience

Prices $275.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-HERPUD1 / HERP Antibody (aa55-83, AP) - LS-C258424 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HERPUD1 / HERP Antibody (aa55-83, APC) - LS-C258425 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HERPUD1 / HERP Antibody (aa55-83, Biotin) - LS-C258426 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HERPUD1 / HERP Antibody (aa55-83, FITC) - LS-C258427 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HERPUD1 / HERP Antibody (aa55-83, PE) - LS-C258429 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HERPUD1 / HERP Antibody - LS-C310594 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-HERPUD1 / HERP Antibody (aa54-83) - LS-C321930 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HERPUD1 / HERP Antibody - LS-C310595 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HERPUD1 / HERP Antibody (aa55-83) - LS-C159824 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
HERPUD1 Antibody western blot of HepG2 cell line lysates (35 ug/lane). The HERPUD1 antibody detected the HERPUD1 protein (arrow).

Anti-HERPUD1 / HERP Antibody (aa55-83, Azide-free, HRP) - LS-C258428 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

HERPUD1 Antibody (2G7) - H00009709-M04 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2G7
Western Blot: HERPUD1 Antibody (2G7) [H00009709-M04] - Analysis of HERPUD1 expression in HepG2 (Cat # L019V1).

HERPUD1 Antibody - NBP2-16809 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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