| Gene Symbol | HERPUD1 |
|---|---|
| Entrez Gene | 9709 |
| Alt Symbol | HERP, Mif1, SUP |
| Species | Human |
| Gene Type | protein-coding |
| Description | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| Other Description | MMS-inducible|homocysteine-inducible endoplasmic reticulum stress-inducible ubiquitin-like domain member 1 protein|homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein|methyl methanesulfonate (MMF)-inducible fragment protein 1 |
| Swissprots | Q96D92 O60644 Q15011 E9PGD1 Q6IAN8 |
| Accessions | BAB19010 EAW82892 EAW82893 EAW82894 Q15011 AB034989 BAB07891 AF055001 AAC09355 AF055003 AAC09357 AF217990 AAG17233 AK223233 BAD96953 AK291565 BAF84254 AK292088 BAF84777 AK302167 BAG63534 AK304800 BAG65550 BC000086 AAH00086 BC008320 AAH08320 BC009739 AAH09739 BC032673 AAH32673 BG685245 BI520043 CD358537 CR457116 CAG33397 D14695 BAA03521 DA581153 DQ837586 ABI18163 DQ891867 ABM82793 EU176642 ABW03443 XM_006721352 XP_006721415 NM_001010989 NP_001010989 NM_001272103 NP_001259032 NM_014685 NP_055500 NM_001010990 |
| Function | Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Could enhance presenilin-mediated beta-amyloid protein 40 generation. {ECO:0000269|PubMed:16289116}. |
| Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:10922362}; Multi-pass membrane protein {ECO:0000269|PubMed:10922362}. |
| Tissue Specificity | Widely expressed; in the brain, expression seems to be restricted to neurons and vascular smooth muscle cells. Present in activated microglia in senile plaques in the brain of patients with Alzheimer disease. |
| Top Pathways | Protein processing in endoplasmic reticulum |
HERPUD1 - MBS1269048 from MyBioSource
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HERPUD1 - MBS1276913 from MyBioSource
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Human HERPUD1 cDNA clone(NM_001010989.1) - CDFH008417 from Creative Biomart
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Human HERPUD1 cDNA clone(NM_001010990.1) - CDFH008418 from Creative Biomart
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Human HERPUD1 cDNA clone(NM_014685.2) - CDFH008419 from Creative Biomart
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Human HERPUD1 ORF Clone(NM_014685.2) - CDCL165946 from Creative Biomart
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Human HERPUD1 ORF Clone(NM_001010989.1) - CDCL165947 from Creative Biomart
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Human HERPUD1 ORF Clone(NM_014685.2) - CDCR298044 from Creative Biomart
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Human HERPUD1 ORF Clone(NM_014685.2) - CDCR298045 from Creative Biomart
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Human HERPUD1 ORF Clone(NM_014685.2) - CDCR298046 from Creative Biomart
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Human HERPUD1 ORF Clone(NM_001010989.1) - CDCR340954 from Creative Biomart
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Human HERPUD1 ORF Clone(NM_001010989.1) - CDCR340955 from Creative Biomart
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Human HERPUD1 ORF Clone(NM_001010990.1) - CDCR340956 from Creative Biomart
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Human HERPUD1 ORF Clone(NM_001010990.1) - CDCR340957 from Creative Biomart
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Human HERPUD1 ORF Clone(NM_014685.2) - CDCR298044 from Creative biogene
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Mouse HERPUD1 ORF clone (NM_001010989.1) - CDCL116683 from Creative biogene
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Mouse HERPUD1 ORF clone (NM_001010990.1) - CDCL116685 from Creative biogene
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Human HERPUD1 ORF Clone (BC009739) - CDCS406456 from Creative biogene
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Human HERPUD1 ORF Clone (BC000086) - CDCS406457 from Creative biogene
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Human HERPUD1 cDNA Clone(NM_001010989.1) - CDFH008417 from Creative biogene
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Human HERPUD1 cDNA Clone(NM_001010990.1) - CDFH008418 from Creative biogene
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Human HERPUD1 cDNA Clone(NM_014685.2) - CDFH008419 from Creative biogene
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