Gene Symbol | HERPUD1 |
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Entrez Gene | 9709 |
Alt Symbol | HERP, Mif1, SUP |
Species | Human |
Gene Type | protein-coding |
Description | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
Other Description | MMS-inducible|homocysteine-inducible endoplasmic reticulum stress-inducible ubiquitin-like domain member 1 protein|homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein|methyl methanesulfonate (MMF)-inducible fragment protein 1 |
Swissprots | Q96D92 O60644 Q15011 E9PGD1 Q6IAN8 |
Accessions | BAB19010 EAW82892 EAW82893 EAW82894 Q15011 AB034989 BAB07891 AF055001 AAC09355 AF055003 AAC09357 AF217990 AAG17233 AK223233 BAD96953 AK291565 BAF84254 AK292088 BAF84777 AK302167 BAG63534 AK304800 BAG65550 BC000086 AAH00086 BC008320 AAH08320 BC009739 AAH09739 BC032673 AAH32673 BG685245 BI520043 CD358537 CR457116 CAG33397 D14695 BAA03521 DA581153 DQ837586 ABI18163 DQ891867 ABM82793 EU176642 ABW03443 XM_006721352 XP_006721415 NM_001010989 NP_001010989 NM_001272103 NP_001259032 NM_014685 NP_055500 NM_001010990 |
Function | Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Could enhance presenilin-mediated beta-amyloid protein 40 generation. {ECO:0000269|PubMed:16289116}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:10922362}; Multi-pass membrane protein {ECO:0000269|PubMed:10922362}. |
Tissue Specificity | Widely expressed; in the brain, expression seems to be restricted to neurons and vascular smooth muscle cells. Present in activated microglia in senile plaques in the brain of patients with Alzheimer disease. |
Top Pathways | Protein processing in endoplasmic reticulum |
Human HERPUD1 full length protein - ab160620 from Abcam
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Human HERPUD1 full length protein - ab160621 from Abcam
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Human HERPUD1 peptide - ab73667 from Abcam
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Human HERPUD1 peptide - ab73668 from Abcam
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Human HERPUD1 protein fragment - ab160622 from Abcam
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Human HERPUD1 protein fragment - ab187459 from Abcam
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HERPUD1 / HERP Antibody Blocking Peptide - LS-E4848 from LifeSpan Bioscience
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HERPUD1 Recombinant Protein - H00009709-P01 from Novus Biologicals
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HERPUD1 Recombinant Protein - H00009709-P02 from Novus Biologicals
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HERPUD1 Partial Recombinant Protein - H00009709-Q01 from Novus Biologicals
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HERPUD1-Antibody-N-term-Blocking-Peptide - BP17228a from Abgent, a WuXi AppTec company
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HERPUD1 protein (His tag) - 80R-3986 from Fitzgerald
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HERPUD1 (1-263, His-tag) - AR51671PU-N from Acris Antibodies
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HERPUD1 (1-263, His-tag) - AR51671PU-S from Acris Antibodies
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HERPUD1 - H00009709-P01-02 from Acris Antibodies
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HERPUD1 - H00009709-P02 from Acris Antibodies
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HERPUD1 - H00009709-P02-02 from Acris Antibodies
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HERPUD1 - H00009709-Q01-10 from Acris Antibodies
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HERPUD1 - H00009709-Q01-25 from Acris Antibodies
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HERPUD1 fusion protein - ag1084 from Proteintech Group
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MIF-1 Tyr - GWB-8C2A08 from Genway Biotech
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Recombinant Human homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1, His-tagged - HERPUD1-628H from Creative Biomart
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HERPuD1, 1-263a Human, His tag, E.coli - ATGP2851 from ATGen
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HERPUD1 Protein - abx163819 from Abbexa
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HERPUD1 (transcript variant 2) - TP300693 from Acris Antibodies
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