MAPK6

Gene Symbol	MAPK6
Entrez Gene	5597
Alt Symbol	ERK3, HsT17250, PRKM6, p97MAPK
Species	Human
Gene Type	protein-coding
Description	mitogen-activated protein kinase 6
Other Description	ERK-3|MAP kinase 6|MAP kinase isoform p97|MAPK 6|extracellular signal-regulated kinase 3|extracellular signal-regulated kinase, p97|p97-MAPK|protein kinase, mitogen-activated 5|protein kinase, mitogen-activated 6
Swissprots	Q16659 B5BU65 Q8IYN8 Q68DH4 B2R945
Accessions	EAW77434 Q16659 AB451301 BAG70115 AF420474 AAL17605 AK313633 BAG36392 BC035492 AAH35492 CR749401 CAH18246 DA109756 DQ891618 ABM82544 DQ894810 ABM85736 L77964 AAA98769 X80692 CAA56709 XM_005254536 XP_005254593 XM_005254537 XP_005254594 XM_005254538 XP_005254595 XM_005254539 XP_005254596 XM_011521782 XP_011520084 NM_002748 NP_002739
Function	Atypical MAPK protein. Phosphorylates microtubule- associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Translocates to the cytoplasm following interaction with MAPKAPK5. {ECO:0000250}.
Tissue Specificity	Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MAPK6 full length protein - ab159217 from Abcam Category Protein Source Wheat germ Species Human

Human MAPK6 protein fragment - ab159218 from Abcam Category Protein Source Wheat germ Species Human

MAPK6 / ERK3 Antibody Blocking Peptide - LS-E20487 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAPK6 / ERK3 Antibody Blocking Peptide - LS-E28032 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ERK3/MAPK6 Protein - H00005597-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human ERK3/MAPK6 Protein - H00005597-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MAPK6 Blocking Peptide - 33R-7769 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ERK3 Blocking Peptide - abx062194 from Abbexa Category Peptide Species Human, Mouse, Bovine, Chicken, Monkey

MAPK6 Peptide - AC21-2908-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

MAPK6 / ERK3 - H00005597-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

MAPK6 / ERK3 - H00005597-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

MAPK6 / ERK3 - H00005597-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MAPK6 / ERK3 - H00005597-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MAPK6 fusion protein - Ag3577 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human MAPK6, GST-tagged - MAPK6-742H from Creative Biomart Category Protein Source E.coli Species Human

ERK3 Blocking Peptide - CBP3300 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Bovine, Chicken, Monkey

ERK3 (D475) Peptide - BS2662P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

ERK3 (K185) Peptide - BS3250P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Mitogen-activated protein kinase 6(MAPK6) - CSB-YP013458HU CSB-EP013458HU CSB-BP013458HU CSB-MP013458HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Human MAPK6 full length protein - ab204165 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

MAPK6 / ERK3 (N-term HIS tag) - TP760513 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

ERK3/MAPK6, Peptide - MBS427900 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Pig, Bovine

ERK3/MAPK6 Recombinant Protein Antigen - NBP1-84806PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Phospho-ERK3-S189-Antibody-Blocking-Peptide - BP3098a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

ERK3-Antibody-C-term-Blocking-Peptide - BP7502a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

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