Gene Symbol | MAP1LC3C |
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Entrez Gene | 440738 |
Alt Symbol | ATG8J, LC3C |
Species | Human |
Gene Type | protein-coding |
Description | microtubule-associated protein 1 light chain 3 gamma |
Other Description | LC3-like protein 2|MAP1 light chain 3-like protein 2|MAP1 light chain 3-like protein 3|MAP1A/MAP1B LC3 C|MAP1A/MAP1B light chain 3 C|autophagy-related protein LC3 C|autophagy-related ubiquitin-like modifier LC3 C|microtubule-associated proteins 1A/1B light chain 3C |
Swissprots | A0PJY8 Q9BXW4 A2RUP0 |
Accessions | EAW70108 Q9BXW4 AF276659 AAK35152 BC127722 AAI27723 BC132986 AAI32987 BC132988 AAI32989 CN260933 XM_005273139 XP_005273196 NM_001004343 NP_001004343 |
Function | Ubiquitin-like modifier that plays a crucial role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2. Recruites all ATG8 family members to infecting bacteria such as S.Typhimurium. {ECO:0000269|PubMed:23022382}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:12740394}. Endomembrane system {ECO:0000269|PubMed:12740394}; Lipid-anchor {ECO:0000269|PubMed:12740394}. Cytoplasmic vesicle, autophagosome membrane {ECO:0000269|PubMed:12740394}; Lipid-anchor {ECO:0000269|PubMed:12740394}. Note=LC3-II binds to the autophagic membranes. |
Tissue Specificity | Most abundant in placenta, lung and ovary. {ECO:0000269|PubMed:12740394}. |
Human LC3C full length protein - ab166539 from Abcam
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MAP1LC3C / LC3C Antibody Blocking Peptide - LS-E5521 from LifeSpan Bioscience
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MAP1LC3C / LC3C Antibody Blocking Peptide - LS-E5522 from LifeSpan Bioscience
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LC3C/MAP1LC3C Recombinant Protein - H00440738-P01 from Novus Biologicals
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LC3C/MAP1LC3C Peptide - P1663 from Novus Biologicals
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LC3-Antibody-APG8C-T48-Blocking-peptide - BP1804e from Abgent, a WuXi AppTec company
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LC3-Antibody-APG8c-N-term-Blocking-Peptide - BP1804a from Abgent, a WuXi AppTec company
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Phospho-LC3CS9-Antibody-Blocking-peptide - BP3457a from Abgent, a WuXi AppTec company
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Phospho-APG8cMAP1LC3CY105-Antibody-Blocking-peptide - BP3691a from Abgent, a WuXi AppTec company
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Phospho-MAP1LC3C-Y105-Antibody-Blocking-peptide - BP3647a from Abgent, a WuXi AppTec company
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Phospho-LC3CT48-Antibody-Blocking-peptide - BP3646a from Abgent, a WuXi AppTec company
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Bi-Phospho-LC3CS137138-Antibody-Blocking-peptide - BP3531a from Abgent, a WuXi AppTec company
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MAP1LC3C - H00440738-P01-10 from Acris Antibodies
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MAP1LC3C - H00440738-P01-25 from Acris Antibodies
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MAP1LC3C Peptide - 7583P from ProSci
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MAP1LC3C fusion protein - Ag17107 from Proteintech Group
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MAP1LC3C fusion protein - ag16283 from Proteintech Group
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Recombinant Human MAP1LC3C, His-tagged - MAP1LC3C-731H from Creative Biomart
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Recombinant Human Microtubule-associated proteins 1A/1B light chain 3C(MAP1LC3C) - CSB-YP887153HU CSB-EP887153HU CSB-BP887153HU CSB-MP887153HU from Cusabio
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MAP1LC3C Peptide - abx164639 from Abbexa
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LC3-Antibody-APG8C-S138-Blocking-peptide - BP1804d from Abgent, a WuXi AppTec company
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LC3-Antibody-APG8C-C-term-Blocking-peptide - BP1804b from Abgent, a WuXi AppTec company
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LC3-Antibody-APG8C-Y105-Blocking-peptide - BP1804f from Abgent, a WuXi AppTec company
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MAP1LC3C Peptide, Human - M34GP09155H from Creative Peptides
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LC3C Recombinant Protein Antigen - NBP2-57604PEP from Novus Biologicals
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