Gene Symbol | MAP1LC3C |
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Entrez Gene | 440738 |
Alt Symbol | ATG8J, LC3C |
Species | Human |
Gene Type | protein-coding |
Description | microtubule-associated protein 1 light chain 3 gamma |
Other Description | LC3-like protein 2|MAP1 light chain 3-like protein 2|MAP1 light chain 3-like protein 3|MAP1A/MAP1B LC3 C|MAP1A/MAP1B light chain 3 C|autophagy-related protein LC3 C|autophagy-related ubiquitin-like modifier LC3 C|microtubule-associated proteins 1A/1B light chain 3C |
Swissprots | A0PJY8 Q9BXW4 A2RUP0 |
Accessions | EAW70108 Q9BXW4 AF276659 AAK35152 BC127722 AAI27723 BC132986 AAI32987 BC132988 AAI32989 CN260933 XM_005273139 XP_005273196 NM_001004343 NP_001004343 |
Function | Ubiquitin-like modifier that plays a crucial role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2. Recruites all ATG8 family members to infecting bacteria such as S.Typhimurium. {ECO:0000269|PubMed:23022382}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:12740394}. Endomembrane system {ECO:0000269|PubMed:12740394}; Lipid-anchor {ECO:0000269|PubMed:12740394}. Cytoplasmic vesicle, autophagosome membrane {ECO:0000269|PubMed:12740394}; Lipid-anchor {ECO:0000269|PubMed:12740394}. Note=LC3-II binds to the autophagic membranes. |
Tissue Specificity | Most abundant in placenta, lung and ovary. {ECO:0000269|PubMed:12740394}. |
LC3C (D1R8V) Rabbit mAb - 14723 from Cell Signaling Technology
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LC3C (D3O6P) Rabbit mAb - 14736 from Cell Signaling Technology
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MAP LC3γ (E-14) - sc-164958 from Santa Cruz Biotechnology
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MAP LC3γ (L-14) - sc-164960 from Santa Cruz Biotechnology
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Anti-LC3C antibody - ab64122 from Abcam
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Anti-LC3C antibody - ab198832 from Abcam
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Anti-LC3C antibody - ab62106 from Abcam
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Anti-LC3C antibody - ab168813 from Abcam
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Anti-LC3C antibody - ab118501 from Abcam
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Anti-LC3C antibody - ab169429 from Abcam
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Anti-LC3C antibody [EPR8076] - ab167421 from Abcam
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Anti-LC3C antibody [EPR8077] - ab150367 from Abcam
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Anti-LC3C antibody - C-terminal - ab191574 from Abcam
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Anti-MAP1LC3C / LC3C Antibody (aa1-30) - LS-C165708 from LifeSpan Bioscience
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Anti-MAP1LC3C / LC3C Antibody (C-Terminus) IHC-plus⢠- LS-B10166 from LifeSpan Bioscience
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Anti-MAP1LC3C / LC3C Antibody (Thr48) IHC-plus⢠- LS-B10155 from LifeSpan Bioscience
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Anti-MAP1LC3C / LC3C Antibody (aa128-144) - LS-C47463 from LifeSpan Bioscience
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Anti-MAP1LC3C / LC3C Antibody (N-Terminus) - LS-C72071 from LifeSpan Bioscience
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Anti-MAP1LC3C / LC3C Antibody - LS-C94282 from LifeSpan Bioscience
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Anti-MAP1LC3C / LC3C Antibody (Thr48, AP) - LS-C237375 from LifeSpan Bioscience
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Anti-MAP1LC3C / LC3C Antibody (Thr48, APC) - LS-C237376 from LifeSpan Bioscience
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Anti-MAP1LC3C / LC3C Antibody (Thr48, FITC) - LS-C237377 from LifeSpan Bioscience
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Anti-MAP1LC3C / LC3C Antibody (Thr48, Biotin) - LS-C237378 from LifeSpan Bioscience
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Anti-MAP1LC3C / LC3C Antibody (Thr48, Azide-free, HRP) - LS-C248760 from LifeSpan Bioscience
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Anti-MAP1LC3C / LC3C Antibody (Thr48, PE) - LS-C237379 from LifeSpan Bioscience
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